ANATOMY AND PHYSIOLOGY: AN INTEGRATIVE A
4th Edition
ISBN: 9781265955021
Author: McKinley
Publisher: MCG
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Chapter 7, Problem 1CSL
The traditional surgical procedure to treat advanced thyroid gland tumors is to remove the affected organ. Some concerns with the results of this surgery were raised regarding the parathyroid glands, which are small attachments on the posterior side of the thyroid gland. Why should the surgeon be concerned about the removal of these glands? A new procedure has been developed to sequester some parathyroid gland tissue into a plastic mesh holder and implant this small holder back into the body. Why is this implant an advantage to the patient?
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You work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs).
Please identify the drug(s) that would be successful in treating hypothyroidism, and explain why and how they would be successful.
Aldosine: A drug that inhibits production of angiotensinogen from the liver
Aldoramine: A drug that inhibits sodium/iodine cotransporter
Thyromine: A drug that stimulates thyroglobulin production
Peroxidine: A drug that inhibits thyroid peroxidase from functioning
Cimigine: A drug that inhibits potassium/iodine cotransporter
Iodimine: A drug that inhibits iodinase from…
You work for a pharmaceutical company where you are assigned the task of creating new drug therapies to treat thyroid disorders such as hyperthyroidism (high levels of T3 and T4) and hypothyroidism (low levels of T3 and T4). Your team has designed a few drugs, and your job is to identify which drug(s) would be successful in treating thyroid disorders based on your knowledge of thyroid hormone synthesis. Below is the list of drugs your team designed (all of these are hypothetical drugs).
Peroxidine: A drug that inhibits thyroid peroxidase from functioning
Cimigine: A drug that inhibits potassium/iodine cotransporter
Iodimine: A drug that inhibits iodinase from functioning
Aldosine: A drug that inhibits production of angiotensinogen from the liver
Aldoramine: A drug that inhibits sodium/iodine cotransporter
Thyromine: A drug that stimulates thyroglobulin production
Identify the drug(s) that would be successful in treating hyperthyroidism and hypothyroidism, and explain why and how they…
Hypothyroidism is a condition in which the thyroid gland fails to
produce adequate amounts crucial hormones. In the early stages,
persons suffering from this condition may be asymptomatic. However,
chronic hypothyroidism may show signs of paleness. Please explain the
physiological reasons for this symptomatology.
Chapter 7 Solutions
ANATOMY AND PHYSIOLOGY: AN INTEGRATIVE A
Ch. 7.1 - Describe the composition of compact bone and...Ch. 7.1 - In what three locations of the body do you find...Ch. 7.2 - What two minerals are stored in bone, and what are...Ch. 7.2 - What are several examples of flat bones in the...Ch. 7.2 - Prob. 5WDYLCh. 7.2 - Prob. 6WDYLCh. 7.2 - Where is red bone marrow found in the adult...Ch. 7.2 - What are the functions of the osteoprogenitor...Ch. 7.2 - What organic and inorganic substances compose bone...Ch. 7.2 - What are the major components of an osteon?
Ch. 7.2 - What are the primary ways that hyaline cartilage...Ch. 7.3 - Where do interstitial and appositional growth of...Ch. 7.4 - Prob. 13WDYLCh. 7.4 - Briefly describe the process by which a long bone...Ch. 7.5 - Prob. 15WDYLCh. 7.5 - What is bone remodeling, where does it occur, and...Ch. 7.5 - Prob. 17WDYLCh. 7.6 - Prob. 18WDYLCh. 7.6 - Prob. 19WDYLCh. 7.6 - Prob. 20WDYLCh. 7.7 - Prob. 21WDYLCh. 7.8 - Prob. 22WDYLCh. 7 - _____ 1. Which bone is formed from intramembranous...Ch. 7 - Prob. 2DYKBCh. 7 - Prob. 3DYKBCh. 7 - Prob. 4DYKBCh. 7 - Prob. 5DYKBCh. 7 - _____ 6. Which long bone structure is correctly...Ch. 7 - _____ 7. Which statement is correct about an...Ch. 7 - Prob. 8DYKBCh. 7 - Prob. 9DYKBCh. 7 - Prob. 10DYKBCh. 7 - Prob. 11DYKBCh. 7 - Prob. 12DYKBCh. 7 - Prob. 13DYKBCh. 7 - Prob. 14DYKBCh. 7 - Prob. 15DYKBCh. 7 - Prob. 16DYKBCh. 7 - Prob. 17DYKBCh. 7 - Prob. 18DYKBCh. 7 - Prob. 19DYKBCh. 7 - Prob. 20DYKBCh. 7 - Prob. 1CALCh. 7 - Prob. 2CALCh. 7 - Prob. 3CALCh. 7 - To identify the approximate age of skeletal...Ch. 7 - In your anatomy and physiology laboratory, you...Ch. 7 - The traditional surgical procedure to treat...Ch. 7 - A fireman fell from a ladder while fighting a fire...Ch. 7 - Prob. 3CSL
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Your friend Bud has the talent to be a star basketball center—if only he weren’t 5 foot 8. Being well- intentioned but ignorant, you start injecting him with growth hormone as he sleeps each night. You. think this is a clever strategy, but after a time you notice that he hasn’t grown an inch. Instead, his jaw and forehead seem to have gotten disproportionately large and his hands and feet are swollen. Explain why the growth hormone didn’t make Bud grow taller and why it had the effect it did. What disease state do these changes mimic?arrow_forwardPituitary gland tumors can secrete excess amount of growth hormone. Describe the signs and symptoms that these tumors cause in an adult experiencing hypersecretion of the growth hormone.arrow_forwardRichard had symptoms of excessive secretion of PTH (high blood calcium levels), and his physicians were certain he had a parathyroid gland tumor. Yet when surgery was performed on his neck, the surgeon could not find the parathyroid glands at all. Where should the surgeon look next to find the tumorous parathyroid gland?arrow_forward
- Thyroid gland is: Choose one: a. Medial on Thorax b. Medial on Cervical c. Superior to Cephalic d. Lateral on Cervicalarrow_forwardThe parents of 14-year old Megan are concerned about her height because she is only 4 fee tall and they are both close to 6 feet tall. After tests by their doctor, certain hormones are prescribed for the girl. What is the probable diagnosis? What hormones are prescribed, and why might the girl expect to reach normal height?arrow_forwardOf the following choices, which is most likely to reduce the risk of a fractured bone in an older person? Question 74 options: a) Hormone replacement therapy in post-menopausal women b) Eating plenty of calcium-containing foods as a teenager c) Ensuring adequate exposure to the sun d) Eating plenty of eggs and dairy foods after the age of 50arrow_forward
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- Thyroid cancer results when the cells in the thyroid gland divide uncontrollably. Individuals who have excessive exposure to radiation may have higher chance of getting thyroid cancer. Thyroid cancer can be treated through surgery, iodine therapy, radiotherapy, and/or chemotherapy. What is the purpose of prescribing thyroxine medication for patients following the surgical removal of the thyroid gland? Select one: a. to decrease TRH and increase TSH levels b. to increase TRH and TSH levels c. to decrease TRH and TSH levels d. to increase TRH and decrease TSH levelsarrow_forwardTumors of the parathyroid gland often result in secretion of excess parathyroid hormone. Considering the function of this hormone, predict the effects of such a tumor. The hormone calcitonin can be used to treat the disease osteoporosis. Explain why this hormone would help to reduce bone loss in patients affected with this disease. 5 The disease diabetes mellitus, type I, is characterized by destruction of the cells that produce insulin in the pancreatic islets. Predict the symptoms and effects of this disease.arrow_forwardAn endocrinal gland with parenchyma consisting of epithelium and neural tissue is under morphological examination. Epithelial trabecules have two types of cells: chromophilic and chromophobic. Identify this organ: O Hypothalamus O Adrenal glands O Thyroid gland O Hypophysis O Parathyroid glandarrow_forward
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