Chapter 7, Problem 12bCP

Summary Introduction

To review:

The following:

1. The process of inactivation of monoamines at the synapse.

2. Clinical manipulation of this process

Introduction:

Monoamines are a class of regulatory molecules that are derived from various amino acids. Some monoamines like dopamine, norepinephrine and epinephrine are obtained or derived from tyrosine, which is also an amino acid. Similar to ACh (acetylcholine), monoamine neurotransmitters are also released by the process of exocytosis which get diffused across the synaptic cleft to reach the postsynaptic cell membrane.