Chapter 5, Problem 8DQ

Summary Introduction

To review:

The human disease modeling using stem cells, can we study vertebrate evolution in a dish. Based on the given data, what questions person may ask.

Introduction:

Many studies reported culturing of organoids, the size of pea that can be maintained in a culture dish for more than a year to study human organogenesis. Moreover, human blastocysts are routinely used to research early human development and interventions for treating infertility. Recently, studies reveal that iPSCs play important role in modeling a complex disease to research mechanisms such as autism spectrum disorders and amyotrophic lateral sclerosis (ALS) leading to direct patient intervention.