Concept explainers
Artemisinin and mefloquine are widely used antimalarial drugs. A ball-and-stick model of artemisinin appears on the cover of this text.
a. Locate the stereogenic centers in both drugs.
b. Label each stereogenic center in mefloquine as
c. What is the maximum number of stereoisomers possible for artemisinin?
d. How are the
e. Can two molecules of artemisinin intermolecularly hydrogen bond to each other?
f. What product is formed when mefloquine is treated with
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