Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 5, Problem 38P
A treatment trial is proposed to test the efficacy of vitamin E as a preventive agent for cancer. One problem with such a study is how to assess compliance among participants. A small pilot study is undertaken to establish criteria for compliance with the proposed study agents. In this study, 10 patients are given 400 IU/day of vitamin E and 10 patients are given similar-sized placebo capsules over a 3-month period. Their serum vitamin E levels are measured before and after the 3-month period, and the change (3-month – baseline) is shown in Table 5.2.
Table 5.2 Change in serum vitamin E (mg/dL) in pilot study
What percentage of the placebo group would be expected to show a change of not more than 0.30 mg/dL?
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Chapter 5 Solutions
Fundamentals of Biostatistics
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