Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 5, Problem 18E

(a)

Summary Introduction

To determine: The positions that cannot tolerate substitutions in the given residues of myoglobin in different organisms.

Concept introduction: If the mutation that exchanges one base for another with a small change in the protein produced is called substitution. Amino acid substitutions in which amino acid residue replacement occurs with another amino acid of similar properties are known as conserved amino acid substitutions. If the amino acid residue is replaced by another residue with similar steric conformation without sharing similar chemical properties, then it is called semi-conserved amino acid.

The given information:

Position12345678910
Human    DIPGHGQEVL
ChickenDIAGHGHEVL
AlligatorKLPEHGHEVI
TurtleDLSAHGQEVI
TunaDYTTMGGLVL
CarpDFEGTGGEVL

(b)

Summary Introduction

To determine: The positions that can tolerate conservative substitutions in the given residues of myoglobin in different organisms.

Concept introduction: Amino acid substitutions in which amino acid residue replacement occurs with another amino acid of similar properties are known as conserved amino acid substitutions. If the amino acid residue is replaced by another residue with similar steric conformation without sharing similar chemical properties, then it is called semi-conserved amino acid.

Given:

Position12345678910
Human    DIPGHGQEVL
ChickenDIAGHGHEVL
AlligatorKLPEHGHEVI
TurtleDLSAHGQEVI
TunaDYTTMGGLVL
CarpDFEGTGGEVL

(c)

Summary Introduction

To determine: The positions that highly variable in the given residues of myoglobin in different organisms.

Concept introduction: Amino acid substitutions in which amino acid residue replacement occurs with another amino acid of similar properties are known as conserved amino acid substitutions. If the amino acid residue is replaced by another residue with similar steric conformation without sharing similar chemical properties, then it is called semi-conserved amino acid.

Given:

Position12345678910
Human    DIPGHGQEVL
ChickenDIAGHGHEVL
AlligatorKLPEHGHEVI
TurtleDLSAHGQEVI
TunaDYTTMGGLVL
CarpDFEGTGGEVL

Blurred answer
Students have asked these similar questions
Identify the type of bond in the following disaccharides. Number your carbons to show work. Explain your answer thoroughly. Draw the number of carbons also.
Draw and explain your answer thoroughly: a. What is the molar mass of aspirin (C9H8O4)?b. What is the mass of 0.00225mol of aspirin?c. How many moles of aspirin are present in 500mg of aspirin?
Geranylgeranyl pyrophosphate 5 is converted by general acid-base catalysis to 6, and then to the natural product 7. For clarity only limited atom numbers are shown, but the main chain carbons are numbered 1 to 16, and the off-chain methyl substituents are numbered 17-20.  A. Based on what you specified in A, use curly arrows on the drawing above to convert 5 to 6, and 6 to 7. Invoke general acids and general bases as needed, and draw in hydrogens as necessary  . B. On the structure of 7, write in the atom numbers for the carbons marked with an asterisk

Chapter 5 Solutions

Fundamentals of Biochemistry: Life at the Molecular Level

Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY