Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Question
Chapter 5, Problem 19E
Summary Introduction
To draw: A phylogenetic tree for the family of homologous proteins whose partial sequences are given.
Given:
Protein A:T L A D K A I S L H D S
Protein B:T L G D K A V S I H E S
Protein C:T L A D K A I S V H D S
Concept introduction: Phylogenetic tree is the diagram that shows the evolutionary relationships between the organisms derived from the common ancestral form. The directed tree with common ancestor is called rooted phylogenetic tree. Unrooted trees are trees with leaf nodes without an ancestor.
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Solution
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Sub
bo Each pictured Lewis structure is invalid. Identify the error in each case.
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Answer Bank
wrong electron total
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octet-rule violation
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[s] mM
V (M/s)
Uninhibited
0.333
1.65 x 107
1.05 x 107
V (M/s) x 10'
Inhibitor A
V (M/s) x 107
Inhibitor B
0.794 x 107
0.40
1.86 x 107
1.21 x 107
0.893 x 107
0.50
2.13 x 107
1.43 x 107
1.02 x 107
0.666
2.49 x 107
1.74 x 107
1.19 x 107
1.0
2.99 x 107
2.22 x 107
1.43 x 107
2.0
3.72 x 107
3.08 x 107
1.79 x 107
For a Michaelis-Menten reaction, k₁-5 x 10'/M-s, k.-2 x 10%/s, and k₂-4 x 10²/s.
a)
Calculate the Ks and KM for this reaction.
b)
Does substrate binding achieve equilibrium or steady state?
Chapter 5 Solutions
Fundamentals of Biochemistry: Life at the Molecular Level
Ch. 5 - Prob. 1ECh. 5 - Prob. 2ECh. 5 - 3. Which peptide has greater absorbance at 280...Ch. 5 - 4. Protein X has an absorptivity of 0.4 mL · mg?1...Ch. 5 - 5. You are using ammonium sulfate to purify...Ch. 5 - Prob. 6ECh. 5 - 7. (a) In what order would the amino acids Arg,...Ch. 5 - Prob. 8ECh. 5 - 9. Explain why a certain protein has an apparent...Ch. 5 - 10. Determine the subunit composition of a protein...
Ch. 5 - 11. Explain why a protein, which has a...Ch. 5 - 12. A protein has an apparent mass of 800 kD by...Ch. 5 - 13. Explain why the dansyl chloride treatment of a...Ch. 5 - 14. Identify the tint residue obtained by Edman...Ch. 5 - 15. A pentapeptide has the sequence NNKNN (using...Ch. 5 - 16. The peptide in Problem 15 was sequenced by...Ch. 5 - 17. In site-directed mutagenesis experiments, Gly...Ch. 5 - 18. Below is a list of the first 10 residues of...Ch. 5 - Prob. 19ECh. 5 - Prob. 20ECh. 5 - Prob. 21CQCh. 5 - Prob. 22CQCh. 5 - 23. What fractionation procedure could be used to...Ch. 5 - Prob. 24CQCh. 5 - 25. Purification tables are often used to keep...Ch. 5 - Prob. 26CQCh. 5 - 27. You must cleave the following peptide into...Ch. 5 - 28. You wish to determine the sequence of a...Ch. 5 - Prob. 29CQCh. 5 - Prob. 30CQCh. 5 - 31. You wish to determine the sequence of a short...Ch. 5 - Prob. 32CQCh. 5 - Prob. 33CQCh. 5 - 34. You wish to sequence the light chain of a...Ch. 5 - Prob. 1MTE
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