Campbell Biology (10th Edition)
10th Edition
ISBN: 9780321775658
Author: Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Publisher: PEARSON
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Chapter 48, Problem 48.3CR
Summary Introduction
To review: The maximum frequency per unit time at which a neuron could fire action potentials (provided that the action potential and refractory period are of the same length).
Introduction:
Action potentials occur when the depolarization shifts the membrane potential sufficiently. Action potentials are magnitude-dependant and they regenerate in the adjacent regions of the membrane.
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For a nerve fibre axoplasmic and extracellular ion concentrations were found to be respectively: Na+, 15 and 115 mM; K+, 90 and 3 mM; Cl-, 10 and 120 mM. Resting potential was -78 mV. Halving the external [Na+] caused a very slight hyperpolarization; doubling external [K+] caused considerable depolarization; halving the external [Cl-] had no effect. In each case the ions were replaced by impermeable salts. What can you deduce (with reasons) about the resting membrane conductances?
f the absolute refractory period of a neuron is 0.7 milliseconds, what is the maximum frequency of action potentials for this neuron?
Based on the graph, how soon could another action potential be easily initiated (at the end of the relative refractory period) after the first stimulus? (Base your answer to this question on the graph below depicting an action potential.)
less than 0.5 msec
1 msec
2 msec
3 msec
4 msec
Chapter 48 Solutions
Campbell Biology (10th Edition)
Ch. 48.1 - Prob. 1CCCh. 48.1 - Describe the basic pathway of information flow...Ch. 48.1 - WHAT IF? How might increased branching of an axon...Ch. 48.2 - Under what circumstances could ions flow through...Ch. 48.2 - WHAT IF? Suppose a cell's membrane potential...Ch. 48.2 - MAKE CONNECTiONS Review Figure 7.10, which...Ch. 48.3 - How do action potentials and graded potentials...Ch. 48.3 - In multiple sclerosis (from the Greek skleros,...Ch. 48.3 - How do both negative and positive feedback...Ch. 48.3 - WHAT IF? Suppose a mutation caused gated sodium...
Ch. 48.4 - Prob. 1CCCh. 48.4 - Some pesticides inhibit acetylcholinesterase, the...Ch. 48.4 - Prob. 3CCCh. 48 - How would severing an axon affect the flow of...Ch. 48 - Suppose you placed an isolated neuron in a...Ch. 48 - Prob. 48.3CRCh. 48 - Prob. 48.4CRCh. 48 - Level 1: Knowledge/Comprehension 1. What happens...Ch. 48 - Level 1: Knowledge/Comprehension 1. What happens...Ch. 48 - Where are neurotransmitter receptors located? (A)...Ch. 48 - Why are action potentials usually conducted in one...Ch. 48 - Which of the following is the most direct result...Ch. 48 - Suppose a particular neurotransmitter causes an...Ch. 48 - WHAT IF? Ouabain, a plant substance used in some...Ch. 48 - Prob. 8TYUCh. 48 - DRAW IT Suppose a researcher inserts a pair of...Ch. 48 - EVOLUTION CONNECTION An action potential is an...Ch. 48 - Prob. 11TYUCh. 48 - WRITE ABOUT A THEME: ORGANIZATION In a short essay...Ch. 48 - Prob. 13TYU
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- View the University of Michigan Webscope (http://openstaxcollege.org/l/nervefiber) to see an electron micrograph of a cross-section of a myelinated nerve fiber. The axon contains microtubules and neurofilaments, bounded by a plasma membrane known as the axolemma. Outside the plasma membrane of the axon is the myelin sheath, which is composed of the tightly wrapped plasma membrane of a Schwann cell. What aspects of the cells in this image react with the stain that makes them the deep, dark, black color, such as the multiple layers that are the myelin sheath?arrow_forwardIf the duration of the absolute refractory period of a neuron is 1 millisecond(ms), how many action potentials are generated by a maximal stimulusin 1 second?arrow_forwardWhat is the equilibrium potential of chloride for a typical neuron? We will use the following ion concentrations and equilibrium potentials: lon Inside concentration (mM) Outside concentration (mM) Equilibrium Potential Sodium 15 145 +60 mV Potassium 125 5 -85 mV Chloride 13 150 -65 mV 60mV -80mV -90mV -65mVarrow_forward
- At the peak of the neuronal action potential, Vm is approximately +50 mV. Assuming normal intracellular and extracellular K+ concentrations ( [K+]o = 4 mM, [K+]i = 150 mM ), what is the driving force (in mV) that acts on K+ ions at the peak of the action potential?arrow_forwardRegarding the passive electrical properties of a neuron, calculate how the EPSP will be affected as determined by the length and time constants, when the ability of the cell membrane has a capacity of charge separation of 75% and a resistance of 60 %. The student investigating the EPSP has determined that the region of the dendrite in which the electrode shows an internal resistance of 0.5 due the diameter of this dendrite proximal to the soma.arrow_forwardIf a neuron is stimulated simultaneously by 2 stimuli at its dendrites (one generates a very large hyperpolarizing potential and the other generates a very small depolarizing potential). What would happen to this neuron? Group of answer choices The summation of these two graded potentials will generate an action potential and this action potential will travel down the axon. Summation of these two graded potentials will cause the membrane potential at the axon hillock to be more negative. These graded potentials will bring the resting membrane potential to 0 mV. These graded potentials with opposite polarity would therefore generate two action potentials and they will travel along this neuron in opposite direction.arrow_forward
- Based upon the changes in permeability seen in the trace below and your knowledge of ion distributions across a cell, predict how ion movements would change during an action potential. Drag and drop each phrase into the appropriate box on the action potential trace. Drag the appropriate labels to their respective targets. Note: not all labels will be used. ►View Available Hint(s) Sodium (Na+) ions move to the axon Sodium (Na) ions move out of the axon Less potassium (K) ions move out of the axon Potassium (K) ions move out of the axon Potassium (K¹) ions move into the axon Sodium (Na) ions stop moving in Membrane potential (mv) +30 +10 0 -10- -30 -50 -70 -90 A PNa 0 PNa 5 6 1 PK Threshold PK 2 Reset Helparrow_forwardYou generate action potentials in a neuron bathed in solution in a petri dish by applying a threshold-level depolarizing stimulus near its axon hillock. If the solution surrounding the neuron contained 5mM K+, 150 mM Na+, and 0 mM Ca2+ which of the following would you expect? The neuron would not be able to propagate action potentials down the entire length of the axon The neuron would not release neurotransmitter from the axon terminal The neurons action potentials would have an unusually long duration The neuron would have a resting membrane potential of zeroarrow_forwardShow a complete circuit diagram of the model of the neuron using the specific numerical values for each component: potassium ion concentration outside: 4.0 mmol/L potassium ion concentration inside: 77.5 mmol/Larrow_forward
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