Laboratory Experiments in Microbiology (11th Edition)
11th Edition
ISBN: 9780321994936
Author: Ted R. Johnson, Christine L. Case
Publisher: PEARSON
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Chapter 42, Problem 3CA
Summary Introduction
To analyse:
A woman with type A, Rh-negative blood can have a healthy baby with type B Rh-positive blood. To analyze the reason why there is no antibody production against the Rh antigen.
Introduction:
Rh factors are antigens that are found on the surface of the red blood cells that also contribute to determine the blood type. Rh incompatibility is a phenomenon that occurs when a mother's Rh factor is different from that of the Rh factor of the foetus that lead to a condition named Erythroblastosis fetalis. This is characterized by the breakdown of red blood cells of the fetus, which is a serious disorder.
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LIST OF THE BLOOD TYPES FROM WHICH THE FOLLOWING PEOPLE COULD RECEIVE, ASSUMING THE RECIPIENTS HAVE BEEN EXPOSED TO Rh antigens:
Recipient:type O+
Recipient: Type B+
Recipient: type A-
Recipient: type AB-
What will happen if an Rh-negative person receives a transfusion of Rh-positive blood?
If a patient will receive a blood transfusion that is not matched to the patient’s blood type, what will happen? Explain briefly.
A woman who is Rh- mates with a man who is Rh+. Since the Rh+ is dominant, what would the fetus's Rh factor type be?A person who is Rh- can donate blood to other people who are either Rh+ or Rh-. However, an Rh+ person can only give blood to who?
Please explain.
Chapter 42 Solutions
Laboratory Experiments in Microbiology (11th Edition)
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- When a mother is Rh-, there is a chance the baby may have hemolytic disease of Newborns. Rh+ mothers do not have this issue. Why? Rh- moms do not have the Rh antigen in their body. A Rh- mom can have a Rh+ baby depending on the male sperm. During pregnancy, Rh- mom can be exposed to her baby's Rh antigen. Let's look at figure a) the first pregnancy. The Rh- mom is pregnant with a Rh+ baby. The baby exposes the mom to Rh antigen during pregnancy. This first baby is delivered and is ok. Figure (b) between pregnancies, the mother is exposed to the foreign antigen Rh and she makes antibodies against Rh. She now has anti-D (anti-Rh) in her body. Figure (c) her second pregnancy with a Rh+ baby. On the next pregnancy that the mom has with a baby. The mom has the anti-D (anti-Rh) antibody in her system. The antibody will attack the baby's RBCS with the Rh antigen on it. When the baby's RBC's are attacked the RBC will hemolyse (hemo=RBC; Lysis=cut). This will result in severe anemia. The lysed…arrow_forwardHow is Rh incompatibility involved in hemolytic disease of the newborn? Is the mother Rh+ or Rh-? Is the fetus Rh+ or Rh-? Why is a second child that is Rh+ more susceptible to attack from the mother’s immune system.arrow_forwardWhy might erythroblastosis fetalis occur when an Rh- mother becomes pregnant with a second Rh+ baby (after exposure to the previous Rh+ baby's blood)? A) Erythroblastosis fetalis can only occur when an Rh+ mother becomes pregnant with an Rh- baby. B) After primary exposure, if the Rh- mother has an Rh+ baby, then antibodies the mom produces can cross the placenta and attack the baby's blood. C) The Rh- mother always produces antibodies to the Rh+ blood, so erythroblastosis fetalis is a condition that can happen to any Rh+ baby (first or subsequent).arrow_forward
- What Rh antigen is present in the red blood cells of this type of blood?arrow_forwarda person with type O has anti-O antibodies?arrow_forward* Type B individuals can receive Type B or Type O blood. Since this individual is Type B+, they can receive Type B+ or Type B- blood. Rh-individuals cannot receive Rh+ blood. An individual with Type B+ blood requires a blood transfusion. Which specific blood types can this individual receive? (Select all that apply.) Type B- Type O- Type O+ Type AB+ Туре АВ- Type B+arrow_forward
- Explain the difference between anti-A/anti-B antibodies and anti-Rh antibodies in terms of their presence in the plasma of individuals.arrow_forwardWhich of the following is characteristic of a person with A+ blood type? 1) produces A antigen, Rh antigen, and B antibody 2) produces B antigen, Rh antigen, and A antibody produces B antigen, no Rh antigen, and no antibody 4) produces A antigen, Rh antigen, and A antibody 5) produces A antigen, B antigen, and B antibodyarrow_forwardSelect all the statements below that are true regarding hemolytic disease of the newborn. If a mother is Rh- and becomes sensitized with anti-Rh antibodies, all subsequent children will be affected Hemolytic disease of the newborn can only occur if the mother is Rh-. If an Rh- mother becomes sensitized, only her subsequent children with Rh+ blood will be affected If a mother is Rh- and her first child is Rh+, the child's RBCS will be attacked by the mother's antibodies.arrow_forward
- If antibody RH is given to a person with a B+ blood type what would happen? If antibody RH is given to a person with a A- blood type what would happen?arrow_forwardDefine the following terms: Antigen, Antibody and Rh factorarrow_forwardIf the thymus of an adult experimental animal is removed, the following observations can be made: (a) No immediate effect occurs, and (b) after 1 year, decreases occur in the number of lymphocytes in the blood, the ability to reject grafts, and the ability to produce antibodies. Explain these observations.arrow_forward
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