Laboratory Experiments in Microbiology (11th Edition)
11th Edition
ISBN: 9780321994936
Author: Ted R. Johnson, Christine L. Case
Publisher: PEARSON
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Chapter 42, Problem 2CT
Summary Introduction
To determine:
The reason for presence of antibodies for A and B blood antigens in a person who has never undergone blood transfusion.
Introduction:
ABO blood group system is the only system that is sued to determine the blood type of the person. The blood group of a person is determined by analyzing the presence of antigens (A or B) on red blood cells. Based on ABO blood system, humans can have four blood types, A blood type, B blood type, O blood type, and AB blood type.
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If a person is given a transfusion with the wrong blood type, what mechanism of
action is responsible for the reaction seen in the body?
O 1) IgE binds to mast cells releasing cytokines
2)
Antigen-antibody complexes (IgG, IgM and IgA) lodge in basement
membranes of tissues, neutrophil degranulation damages the tissues
O 3) T cells respond to the inappropriate cells
4)
IgG and IgM bind to cells stimulating complement, triggering cell lysis
Draw the antigens on the red blood cell below for someone who is A+. Draw the antibodies for this person in the surrounding plasma. What type of blood can this person receive and why?
Identify the specific blood type incompatibility shown in Chapter 3 of the animation.
Agglutination of donor's A antigens by recipient's anti-A antibodies.
Agglutination of donor's B antigens by recipient's anti-B antibodies.
Agglutination of donor's A antigens by recipient's anti-B antibodies.
○ Agglutination of donor's B antigens by recipient's anti-A antibodies.
Chapter 42 Solutions
Laboratory Experiments in Microbiology (11th Edition)
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- Blood Types Are Determined by Cell-Surface Antigens Is it more important that transfused blood have antigens that will not react with the recipients antibodies, or antibodies that will not react with the recipients antigens?arrow_forwardWhat type(s) of antibodies does the plasma contain for each of the following blood types? (a) type A (b) type B (c) type AB (d) type Oarrow_forwardBefore a recipient is given blood transfusion, the medical team must first learn the patient's blood type and then find a suitable , or "matching", donor. This is necessary because of the A, B, and Rh antigens on the surface of the donor erythrocytes and the presence of preformed antibodies in the recipient's blood. True or False?arrow_forward
- Which of the following is characteristic of a person with A+ blood type? 1) produces A antigen, Rh antigen, and B antibody 2) produces B antigen, Rh antigen, and A antibody produces B antigen, no Rh antigen, and no antibody 4) produces A antigen, Rh antigen, and A antibody 5) produces A antigen, B antigen, and B antibodyarrow_forwardA person with type A+ blood gets a transfusion with type O- blood. What is most likely to happen to the recipient? A) The recipient's blood will agglutinate (clump) due to the presence of natural antibodies in the recipient's blood. B) Nothing because the donor's blood is compatible with the recipient's blood. C) The recipient's blood will agglutinate (clump) due to the presence of natural antigens on the recipient's blood cells.arrow_forwardWhy might erythroblastosis fetalis occur when an Rh- mother becomes pregnant with a second Rh+ baby (after exposure to the previous Rh+ baby's blood)? A) Erythroblastosis fetalis can only occur when an Rh+ mother becomes pregnant with an Rh- baby. B) After primary exposure, if the Rh- mother has an Rh+ baby, then antibodies the mom produces can cross the placenta and attack the baby's blood. C) The Rh- mother always produces antibodies to the Rh+ blood, so erythroblastosis fetalis is a condition that can happen to any Rh+ baby (first or subsequent).arrow_forward
- In terms of antigens and antibodies, explain why O- is considered a universal donor and why AB+ is considered a universal recipient. Even so, why can’t whole blood O- be donated to a person of type AB+ blood?arrow_forwardDescribe the structural differences associated with antigens displayed on the surface of red blood cells. To receive full credit, you have to provide specific descriptions for each blood type and explain the cause of these differences.arrow_forwardAlong with platelet plug formation, which two mechanisms contribute to hemostasis?arrow_forward
- List the four ABO blood types. For each one, list its red blood cell surface antigen(s) and plasma antibody (antibodies).arrow_forwardTest Taker/MonitorLaunch.aspx?id%=EAB1291A-8287-4915-B4FD-3F4F9CEB9 chaspx7id%3DEAB1291A-8287-4915-BAFD-3F4F9CEB9101-Googlef Question 6 Which white blood cell type is correctly matched with its function or feature? Review Later [2.857 proper A) O neutrophils: primarily works with adaptive immune system as an antigen presenting cell [2.857 [2.8571 B) O basophils: outside the blood, differentiate into macrophages (2.85714 and dendritic cells [2.85714 [2.857142 C) O macrophages: antibody-producing cells (2.857142 D) O dendritic cells: works with adaptive immune system as an [2.8571429 antigen presenting cell (2.8571429 TES E) specific chemicals such as histamine monocyte: promotes inflammatory response via release of Time A Review Later Total Pro Question 7 O Type here to searcharrow_forwardDescribe the structural differences associated with antigens displayed on the surface of red blood cells. Please provide specific descriptions for each blood type and explain the cause of this differencesarrow_forward
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