Laboratory Experiments in Microbiology (11th Edition)
Laboratory Experiments in Microbiology (11th Edition)
11th Edition
ISBN: 9780321994936
Author: Ted R. Johnson, Christine L. Case
Publisher: PEARSON
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Chapter 42, Problem 1CA
Summary Introduction

To analyze:

Hemolytic disease of the newborn and its prevention by RhoGAM

Introduction:

Hemolytic disease of the newborn (HDN) or the Rh disease as it is commonly called is caused due to the mismatch of blood types in between a baby and its mother. Mostly the second baby having a mismatch of blood type from that of the mother is prone to this disease. However, medications like RhoGAM are available for treating the condition in both baby and mother.

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How can the hemolyticdisease of the newborn beprevented?
Trisha has another baby with Johnny (Charlotte's father). Shortly after the birth of this baby, the newborn was immediately transported to the Neonatal Intensive Care Unit.  The doctors informed Trisha that this baby was suffering from hemolytic disease of the newborn.  Explain (i) how hemolytic disease of the newborn arose in Trisha’s second child, (ii) how it should have been prevented, and (iii) the mechanism of action of the preventative treatment for this condition.  Please LABEL the parts of your answer to this question (i), (ii), and (iii).
Why does hemagglutination occur and how can it be used in the clinical laboratory?
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