EBK LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 8220103935432
Author: Sadava
Publisher: MAC HIGHER
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Chapter 41.2, Problem 2R
Summary Introduction
To review:
The reason as to why a speck of dust landing on the skin does not lead to an innate immune response, while a bacterium does.
Introduction:
The immune system can be divided into innate immunity and the adaptive immunity. Innate immunity is referred as the first line of defense and mainly includes physical and chemical barriers. It is nonspecific and acts on all potential harmful invaders without discrimination.
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Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly
The pKa values for the peptide's side chains, terminal amino groups, and carboxyl groups are provided in the table.
Amino acid Amino pKa Carboxyl pKa Side-chain pKa
glutamate
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histidine
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tryptophan
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serine
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glycine
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leucine
9.60
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arginine
9.04
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proline
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1.99
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net charge at pH 3:
Calculate the net charge of the molecule at pH 8.
net charge at pH 8:
Calculate the net charge of the molecule at pH 11.
net charge at pH 11:
Estimate the isoelectric point (pl) for this peptide.
pl:
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EBK LIFE: THE SCIENCE OF BIOLOGY
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