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Concept introduction: Purines and pyrimidines constitute the nucleotides of the DNA. Adenine and guanine are the purines. Cytosine and thymine are the pyrimidines. In a double-stranded DNA, adenine always bond with thymine and guanine always bond with cytosine. Chargaff’s rule states that in a double-stranded DNA, the number of purines is always equal to the number of pyrimidines that is the ratio of purines to pyrimidines should always be 1:1. Also the amount of adenine must be equal to the amount of thymine, and amount of guanine must be equal to the amount of thymine based on the purine and pyrimidine pairing rule.
To explain: The reason why the results are peculiar.
Concept introduction: Purines and pyrimidines constitute the nucleotides of the DNA. Adenine and guanine are the purines. Cytosine and thymine are the pyrimidines. In a double-stranded DNA, adenine always bond with thymine and guanine always bond with cytosine. Chargaff’s rule states that in a double-stranded DNA, the number of purines is always equal to the number of pyrimidines that is the ratio of purines to pyrimidines should always be 1:1. Also the amount of adenine must be equal to the amount of thymine, and amount of guanine must be equal to the amount of thymine based on the purine and pyrimidine pairing rule.
To explain: The reasons why the values vary largely.
Concept introduction: Purines and pyrimidines constitute the nucleotides of the DNA. Adenine and guanine are the purines. Cytosine and thymine are the pyrimidines. In a double-stranded DNA, adenine always bond with thymine and guanine always bond with cytosine. Chargaff’s rule states that in a double-stranded DNA, the number of purines is always equal to the number of pyrimidines that is the ratio of purines to pyrimidines should always be 1:1. Also the amount of adenine must be equal to the amount of thymine, and amount of guanine must be equal to the amount of thymine based on the purine and pyrimidine pairing rule.
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