Organic Chemistry: Structure and Function
Organic Chemistry: Structure and Function
8th Edition
ISBN: 9781319079451
Author: K. Peter C. Vollhardt, Neil E. Schore
Publisher: W. H. Freeman
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Chapter 4, Problem 44P

(a)

Interpretation Introduction

Interpretation:The more stable form from the two needs to be determined.

Concept Introduction:Checking the hydroxyl groups for equatorial positions (no diaxial interaction).

(b)

Interpretation Introduction

Interpretation:The free energy difference corresponding to the given equilibrium ratio needs to be determined.

Concept Introduction:The free energy difference corresponding to the given equilibrium ratio(K) is calculated using the formula:

  ΔG0=1.36log(K) .

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Predict the major products of both organic reactions. Be sure to use wedge and dash bonds to show the stereochemistry of the products when it's important, for example to distinguish between two different major products. esc esc Explanation Check 2 : + + X H₁₂O + Х ง WW E R Y qab Ccaps lock shift $ P X Click and drag to start drawing a structure. © 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility Bil T FR F18 9 G t K L Z X V B N M control opption command command T C d
Draw the Markovnikov product of the hydrohalogenation of this alkene. this problem. Note for advanced students: draw only one product, and don't worry about showing any stereochemistry. Drawing dash and wedge bonds has been disabled for caps lock Explanation Check 2 W E R + X 5 HCI Click and drag to start drawing a structure. © 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility Bil Y F G H K L ZZ X C V B N M control opption command F10 F10 command 4 BA Ar C
I don't understand why the amide on the top left, with the R attached to one side, doesn't get substituted with OH to form a carboxylic acid.  And if only one can be substituted, why did it choose the amide it chose rather than the other amide?
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