Chapter 4, Problem 15PIAT

Summary Introduction

To review:

The Chargaff’s observations helped Watson and Crick to propose the complementary base pairing in double-stranded DNA model. The similar ratios of nucleotides if Chargaff had used RNA instead and reasons behind it.

Introduction:

Watson and Crick used Chargaff’s data of 1:1 between adenine:thymine (A:T) and guanine:cytosine (G:C) to establish the concept of complementary base pairing by DNA (deoxyribonucleic acid) double-helix model.