Biological Science (6th Edition)
Biological Science (6th Edition)
6th Edition
ISBN: 9780321976499
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Emily Taylor, Greg Podgorski, Jeff Carmichael
Publisher: PEARSON
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Chapter 4, Problem 14PIAT

QUANTITATIVE In 1951, Erwin Chargaff was accumulating data on the molar ratios of nucleotides using DNA obtained from a variety of sources. Some of these data are provided in the following table:

Molar Ratios in DNA Preparations
Source A:G T:C A:T G:C purines:pyrimidines
Ox 1.29 1.43 1.04 1.00 1.10
Human 1.56 1.75 1.00 1.00 1.0
Chicken 1.45 1.29 1.06 0.91 0.99
Salmon 1.43 1.43 1.02 1.02 1.02
Wheat 1.22 1.18 1.00 0.97 0.99
Yeast 1.67 1.92 1.03 1.20 1.0

Source: Chargaff, E. 1951. Federal Proceedings 10" 654–659.

Compare the molar ratios presented from each organism tested and between different organisms. Explain how these data could be used to show that Levene'stetranucleotide model is incorrect. What do they imply about the primary structure of DNA in different organisms?

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