(a)
To determine: The effect of substitution of valine in the place of glutamate at the 6th position of β-chain.
Introduction: The condition where there’s an inadequate amount of red blood cells are present in the body is called “sickle cell anemia.” During the presence of an insufficient amount of red blood cells in the circulatory system leads to the transportation of a deficient amount of oxygen to various parts of the body. In this disease, the red blood cells become rigid and sticky and they shaped like “sickle” or as the “crescent moons.”
(b)
To determine: The specific amino acid which would be less likely like valine in the harm of the hemoglobin if it changed to the glutamate at the 6th position of the β-chain.
Introduction: The condition where there’s an inadequate amount of red blood cells are present in the body is called “sickle cell anemia.” During the presence of an insufficient amount of red blood cells in the circulatory system leads to the transportation of a deficient amount of oxygen to various parts of the body. In this disease, the red blood cells become rigid and sticky and they shaped like “sickle” or as the “crescent moons.”
(c)
To explain: The similarity in the function and structure of proteins after the difference in various points of the sequence of the amino acid.
Introduction: The condition where there’s an inadequate amount of red blood cells are present in the body is called “sickle cell anemia.” During the presence of an insufficient amount of red blood cells in the circulatory system leads to the transportation of a deficient amount of oxygen to various parts of the body. In this disease, the red blood cells become rigid and sticky and they shaped like “sickle” or as the “crescent moons.”
Want to see the full answer?
Check out a sample textbook solutionChapter 3 Solutions
Becker's World of the Cell (9th Edition)
- a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involvedarrow_forwardIf you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose B. Dose; Decrease dose C. Dose; Do not change dose D. Interval; Increase the interval between doses (give the drug less frequently) E. Interval; Decrease the interval between doses (give the drug more frequently) F. Interval; Do not change the intervalarrow_forwardWhat percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the matharrow_forward
- Briefly explain the 6 domain of interprofessional collaboration: Role clarification, Team functioning, Interprofessional communication, Patient/client/family/community-centered care, Interprofessional conflict resolution, Collaborative leadership. Provide a specific negative events that nursing student would observe in a clinical setting for each domain.arrow_forwardwhat is an intermittent water course and what kind of fish habitat it would providearrow_forwardwhy are native freshwater mussels are an important part of great lakes ecosystemarrow_forward
- what morphological features differentiate the lamprey species and other species in the great lakesarrow_forwardThere are a wide range of therapeutic applications available as options for patients. Medical professionals should be aware of these applications so they can make informed recommendations to patients. To gain a better understanding of some therapeutic applications and how they are related to RNA and mRNA, research long non-coding RNA. Respond to the following in a minimum of 175 words: What is lncRNA and what does it do? How does IncRNA differ from mRNA? What are some therapeutic applications associated with lncRNA? Think about possible future uses of this application. What are the advantages and disadvantages of this application and its continued use?arrow_forwardfour fish or mussel species that are native to the great lakesarrow_forward
- There are a wide range of therapeutic applications available as options for patients. Medical professionals should be aware of these applications so they can make informed recommendations to patients. To gain a better understanding of some therapeutic applications and how they are related to RNA and mRNA, research long non-coding RNA. Respond to the following in a minimum of 175 words: What is lncRNA and what does it do? How does IncRNA differ from mRNA? What are some therapeutic applications associated with lncRNA? Think about possible future uses of this application. What are the advantages and disadvantages of this application and its continued use?arrow_forwardfour physial characteristics of a fish or a mussel that would help you identify it to a speciesarrow_forwarddescribe what you would do in this situation, you are working ona. river and it will take 20 minutes by boat to get back to the field truck, you are 1 hour from finishing the field work on the last day of field trip. you hear thunder int he dsitnace, what did you do?arrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage LearningAnatomy & PhysiologyBiologyISBN:9781938168130Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark WomblePublisher:OpenStax CollegeBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningBiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning