Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 3, Problem 3.4PS

(a)

Summary Introduction

To determine: The effect of substitution of valine in the place of glutamate at the 6th position of β-chain.

Introduction: The condition where there’s an inadequate amount of red blood cells are present in the body is called “sickle cell anemia.” During the presence of an insufficient amount of red blood cells in the circulatory system leads to the transportation of a deficient amount of oxygen to various parts of the body. In this disease, the red blood cells become rigid and sticky and they shaped like “sickle” or as the “crescent moons.”

(b)

Summary Introduction

To determine: The specific amino acid which would be less likely like valine in the harm of the hemoglobin if it changed to the glutamate at the 6th position of the β-chain.

Introduction: The condition where there’s an inadequate amount of red blood cells are present in the body is called “sickle cell anemia.” During the presence of an insufficient amount of red blood cells in the circulatory system leads to the transportation of a deficient amount of oxygen to various parts of the body. In this disease, the red blood cells become rigid and sticky and they shaped like “sickle” or as the “crescent moons.”

(c)

Summary Introduction

To explain: The similarity in the function and structure of proteins after the difference in various points of the sequence of the amino acid.

Introduction: The condition where there’s an inadequate amount of red blood cells are present in the body is called “sickle cell anemia.” During the presence of an insufficient amount of red blood cells in the circulatory system leads to the transportation of a deficient amount of oxygen to various parts of the body. In this disease, the red blood cells become rigid and sticky and they shaped like “sickle” or as the “crescent moons.”

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