Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported: Table 3.7 Attack rate for influenza by age and treatment group Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the probability that at least one child among the 3 will get influenza?
Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported: Table 3.7 Attack rate for influenza by age and treatment group Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the probability that at least one child among the 3 will get influenza?
Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported:
Table 3.7 Attack rate for influenza by age and treatment group
Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the probability that at least one child among the 3 will get influenza?
Problem 5 (
Marybeth is also interested in the experiment from Problem 2 (associated with the enhancements for Captain
America's shield), so she decides to start a detailed literature review on the subject. Among others, she found
a paper where they used a 2"(4-1) fractional factorial design in the factors: (A) shield material, (B) throwing
mechanism, (C) edge modification, and (D) handle adjustment. The experimental design used in the paper is
shown in the table below.
a.
Run
A
B
с
D
1
(1)
-1
-1
-1
1
2
a
1
-1
-1
1
3
bd
-1
1
-1
1
4
abd
1
1
-1
1
5
cd
-1
-1
1
-1
6
acd
1
-1
1
-1
7
bc
-1
1
1
-1
abc
1
1
1
-1
paper?
s) What was the generator used in the 2"(4-1) fractional factorial design described in the
b.
Based on the resolution of this design, what do you think about the generator used in the
paper? Do you think it was a good choice, or would you have selected a different one? Explain your
answer in detail.
Suppose we wish to test the hypothesis that women with a sister’s history of breast cancer are at higher risk of developing breast cancer themselves. Suppose we assume that the prevalence rate of breast cancer is 3% among 60- to 64-year-old U.S. women, whereas it is 5% among women with a sister history. We propose to interview 400 women 40 to 64 years of age with a sister history of the disease. What is the power of such a study assuming that the level of significance is 10%?
I only need help writing the null and alternative hypotheses.
4.96 The breaking strengths for 1-foot-square samples of a particular synthetic fabric are approximately normally distributed with a mean of 2,250 pounds per square inch (psi) and a standard deviation of 10.2 psi. Find the probability of selecting a 1-foot-square sample of material at random that on testing would have a breaking strength in excess of 2,265 psi.4.97 Refer to Exercise 4.96. Suppose that a new synthetic fabric has been developed that may have a different mean breaking strength. A random sample of 15 1-foot sections is obtained, and each section is tested for breaking strength. If we assume that the population standard deviation for the new fabric is identical to that for the old fabric, describe the sampling distribution forybased on random samples of 15 1-foot sections of new fabric
Chapter 3 Solutions
WebAssign for Rosner's Fundamentals of Biostatistics, 8th Edition [Instant Access], Single-Term
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Introduction to experimental design and analysis of variance (ANOVA); Author: Dr. Bharatendra Rai;https://www.youtube.com/watch?v=vSFo1MwLoxU;License: Standard YouTube License, CC-BY