Principles of Human Physiology (6th Edition)
Principles of Human Physiology (6th Edition)
6th Edition
ISBN: 9780134169804
Author: Cindy L. Stanfield
Publisher: PEARSON
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Chapter 3, Problem 28E

As you know, fatty acids can be oxidized to provide energy for making ATP. This process begins with a set of reactions known as the fatty acid oxidation cycle, or beta oxidation. Before entering the cycle, a fatty acid reacts with coenzyme A to form a molecule called fatty acyl CoA. This molecule then enters the cycle and continues to go through it until all its carbons have been eliminated, as shown on the following page. From your examination of this diagram, answer the following questions for a 1 2-carbon fatty acid.

  1. How many acetyl CoA molecules will be produced by beta oxidation of this fatty acid? How many ATP molecules can be produced from each acetyl CoA molecule that goes through the Krebs cycle and oxidative phosphorylation?
  2. How many NAD+ and FAD molecules will be reduced? (Hint: How many bonds must be broken to split a 12-carbon fatty acid into acetyl CoA molecules?)
  3. How many ATP molecules will be produced per each NADH + H+ and each FADH2 molecule that provides electrons to the electron transport system?
  4. It takes two ATP molecules to get the cycle started. Based on this information and your answers to the previous questions, how many ATP molecules can be generated from a 1 2-carbon fatty acid?
  5. Chapter 3, Problem 28E, As you know, fatty acids can be oxidized to provide energy for making ATP. This process begins with

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