
Concept explainers
Interpretation:
Methamphetamine acts whether agonist or antagonist has to be determined.
Concept Introduction:
Neurotransmitters: Neurotransmitters are chemicals that transmit messages from the nervous system to the target cell. They are the chemical messagers where the electrical signal from the nervous system is travelled from one neuron to another to reach the target cell.
Drugs: Drugs are molecules which are taken from an external source to change the normal functioning of the body. The action of drug is in molecular level and the design of many drugs are in such a way that it mimics a particular neurotransmitter or hormone. Drugs bind with receptors showing an increased or decreased effect.
There are two types of drugs and they are agonist and antagonist.
- 1. Agonists are chemical substance that binds with a receptor so that it activates the receptor for producing or prolonging its normal biochemical response.
- 2. Antagonists are chemical substance that binds with a receptor so that it blocks or inhibits the normal biochemical response of a particular receptor.
Dopamine is a neurotransmitter has a key role in the brain. It is required for many processes such as emotional response, controlling of movements and experiencing pain and pleasure. Dopamine induces a highly satisfied feeling.
Methamphetamine causes behavioral change similar to schizophrenia and is an agonist where it increases the dopamine level in the brain.

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Chapter 28 Solutions
Pearson eText Fundamentals of General, Organic, and Biological Chemistry -- Instant Access (Pearson+)
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- 5. Which one is the major organic product obtained from the following reaction sequence? First, equimolar amounts of cyclopentanone and LDA are mixed at -78°C. Then propionaldehyde (propanal) is added. Addition of aqueous acid completes the process. LDA, -78°C. 1. 2. H₂O* H A B H 0 D H H Earrow_forward2. Which one is the major organic product obtained from the following reaction? NaOH, H₂O heat A B C D Earrow_forwardCH3CH2CHO + propanal PhCH2CHO 2-phenylacetaldehyde mixture of four products NaOH 10. In the crossed aldol reaction of propanal and 2-phenylacetaldehyde shown above, a mixture of four products will be formed. Which ONE of the compounds below will NOT be formed in this crossed aldol reaction? OH Ph A H OH OH Ph H B OH OH H H H Ph Ph C Ph D Earrow_forward
- An organic chemist ordered the wrong item. She wanted to obtain 1-hydroxy-2-butanone, butinstead ordered 2-hydroxybutyraldehyde. As a good biochemist, show how the organic chemistcould use biological catalysis to make her desired compound.arrow_forwardPredict the products of aldolase catalyzing the reaction with acetone and (S)-3-hydroxybutyraldehyde.arrow_forwardA cancer patient undergoing chemotherapy is taking a protein kinase inhibitor drug. The patientis an avid marathon runner and does not want to miss his upcoming race. Is it a good idea forthis patient to attempt a marathon while on this medication? Explain why or why not.arrow_forward
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