ANATOMY & PHYSIOLOGY 4/E PAC 1 SEMESTER
ANATOMY & PHYSIOLOGY 4/E PAC 1 SEMESTER
4th Edition
ISBN: 9781265061173
Author: McKinley
Publisher: MCG CUSTOM
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Chapter 27.6, Problem 17WDYL
Summary Introduction

To determine:

The molecular structure out of ( VLDLs , LDLs , and HDLs ) responsible for the transportation of cholesterol from peripheral tissues to the liver.

Concept introduction:

Cholesterol molecules are not soluble in blood, so the cholesterol molecules can only be transported with the help of “water-soluble proteins”. There are three types of proteins for the transportation of lipids through the blood: VLDLs “Very low-density lipoproteins”, LDLs “Low-density lipoproteins”, HDLs and “High-density proteins”.

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Which lipoprotein particles contain “good” and “bad” cholesterol, and why are these terms used?
1) The major function of high density lipoprotein (HDL) is to, choose all correct answers. (A)   bind high density lipoprotein (HDL). (B)    transport cholesterol to peripheral tissues. (C)    serve as a precursor for cholesterol biosynthesis. (D)   transport cholesterol from peripheral tissues to liver.  (E)    serve as a site for the esterification of cholesterol. 2). Individual with the genetic disease of Familial hypercholesterolemia have higher levels of cholesterol in the blood, which of the following could cause this disease: (A)   deregulated biosynthesis of low-density lipoprotein (LDL) receptors (B)    high dietary cholesterol (C)    plaque formation in the arteries. (D)   high cholesterol biosynthesis in liver tissue. (E)    deregulated biosynthesis of low-density lipoprotein (LDL)  3) The enzyme inorganic pyrophosphatase utilizes ____ as its substrate.            A). ATP            B). ADP            C). AMP            D). PPi            E). phosphate
Which of the following statements regarding the synthesis and metabolism of lipoprotein complexes are TRUE?1) pre-HDLs are synthesized only in the liver2) VLDLs are metabolized by lipoprotein lipase3) HDLs are produced as derivatives in VLDL metabolism4) a high serum level of LDL increases the risk of myocardial infarction5) HDLs carry cholesterol esters and clear up the excess of cholesterol from extrahepatic tissues

Chapter 27 Solutions

ANATOMY & PHYSIOLOGY 4/E PAC 1 SEMESTER

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