Figure 27.5 If a Hox 13 gene in a mouse was replaced with a Hox 1 gene, how might this alter animal development?
To analyze:
The development of the mouse if the Hox13 gene is replaced by the Hox1 gene.
Introduction:
Homeotic genes are the regulatory genes that control the development of body structures. One such set of genes called the Hox genes are the group of the related genes that control the body plan of an embryo along the head-tail axis.
Explanation of Solution
Among the vertebrates, humans and mice show the duplication of the Hox genes over the period of evolution. They are present in the four gene clusters on four different chromosomes called Hox- A, Hox- B, Hox- C and Hox- D. The genes within these clusters express in certain body segments at a particular stage of development.
The genes show homology in humans and mice and the genes Hox 1-4 are involved in the development of the head and the genes Hox 9-13 are involved in the development of the limbs in humans and the tail in the mouse. If a Hox- 13 gene is replaced by a Hox- 1 gene in the mouse, it might develop two heads due to the presence of two Hox-1 genes and lack a tail due to the missing Hox- 13 gene.
Thus, the replacement of Hox- 13 genes by Hox- 1 gene in the mouse can lead to the formation of a mouse with two heads and no tail.
Want to see more full solutions like this?
Chapter 27 Solutions
Biology 2e
Additional Science Textbook Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Biological Science (6th Edition)
Human Physiology: An Integrated Approach (8th Edition)
Concepts of Genetics (12th Edition)
Campbell Essential Biology (7th Edition)
Anatomy & Physiology (6th Edition)
- How might differential expression of and regulation by Hox genes contribute to mosaic evolution in which different segments of an animalbody plan evolve different morphologies?arrow_forwardThis question is about mammals. a) What is the one defining characteristic that determines a mammal? b) Compare and contrast the three types of mammals with respect to fetal development and birth: the monotremes (such as the platypus), the marsupials (such as kangaroos), and the placentals (such as humans or dogs). That is, where does most of the early development occur, how is the young mammal introduced to the world, and how does the young obtain nourishment once introduced to the world?arrow_forwardWhich statement about Hox genes is false? a. They are expressed in similar patterns in the embryos of both mice and flies. b. They include a conserved region of base pairs called the homeobox. c. They are arranged in similar clusters of genes in both mice and flies. d. They are part of the so-called genetic toolkit. e. Because of their important functional roles, they evolved rapidly in both mammals and flies.arrow_forward
- by looking at the picture above, describe the events that take place during fertilization of an embryoarrow_forwardWhy is it likely that Hox genes have played a major rolein the evolution of novel morphological forms?arrow_forwardWhy is knowing information about embryo development important?arrow_forward
- The toolkit genes generally regulate_____ [A]_____ in order to direct development. Other developmental decisions are regulated _____[B]_____, as we saw in sex determination in flies. *Hint: these are steps in the Central Dogma? Give typing answer with explanation and conclusionarrow_forwardGiven the distribution of Hox genes among animals, what would you predict about the number and type of Hox genes in the common ancestor of all animals?arrow_forwardIs parental care of a species a factor that affects embryological development? If so, how?arrow_forward
- Which statement is true of hox genes? Group of answer choices A. they regulate development of body regions and are found in all animals B. they control the functioning of cells and are found in all life C. they control growth and development in plants D. they are only found in insects and control segmentationarrow_forwardBriefly describe how the HoxC-6 gene affects vertebrate development.arrow_forwardHow does von baer's law of development relates with the development of the frog embryo? evidences?arrow_forward
- Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxBiology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage LearningBiology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning
- Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning