Organic Chemistry - Standalone book
Organic Chemistry - Standalone book
10th Edition
ISBN: 9780073511214
Author: Francis A Carey Dr., Robert M. Giuliano
Publisher: McGraw-Hill Education
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Chapter 26.12, Problem 20P
Interpretation Introduction

Interpretation:

The structure of the PTH derivative isolated in the second Edman cycle of the tetrapeptide Val-Phe-Gly-Ala is to be given.

Concept Introduction:

Edman degradation uses phenyl isothiocyanate to cleave the bond between the N-terminal amino acid and the rest of the peptide chain.

Anhydrous conditions ensure that other amide bonds are not cleaved.

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