The product(s) of each of the given reactions are to be determined. Concept Introduction: 1 -fluoro-2,4-dinitrobenzene is used to protect the anime group of an amino acid. Hydrolysis of a peptide with a 1 -fluoro-2,4-dinitrobenzene protected N terminus results in hydrolysis of amide bonds in the peptide. Treatment of a peptide with phenyl isothiocyanate protects the N terminus of the chain. Subsequent treatment with a strong acid in anhydrous conditions cleaves only the amide bond between the protected amino acid residue and the rest of the peptide chain. Benzyloxycarbonyl chloride is used to protect the amine group of an amino acid. N,N'-dicyclohexylcarbodiimide is used as a dehydrating agent in peptide and ester formation reactions. Hydrogenolysis with hydrogen over palladium is used for deprotection of N terminus.

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Answer 1

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26, Problem 38P

Interpretation Introduction

Interpretation:

The product(s) of each of the given reactions are to be determined.

Concept Introduction:

1-fluoro-2,4-dinitrobenzene is used to protect the anime group of an amino acid.

Hydrolysis of a peptide with a 1-fluoro-2,4-dinitrobenzene protected N terminus results in hydrolysis of amide bonds in the peptide.

Treatment of a peptide with phenyl isothiocyanate protects the N terminus of the chain. Subsequent treatment with a strong acid in anhydrous conditions cleaves only the amide bond between the protected amino acid residue and the rest of the peptide chain.

Benzyloxycarbonyl chloride is used to protect the amine group of an amino acid.

N,N'-dicyclohexylcarbodiimide is used as a dehydrating agent in peptide and ester formation reactions.

Hydrogenolysis with hydrogen over palladium is used for deprotection of N terminus.

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Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26, Problem 38P

Interpretation Introduction

Interpretation:

The product(s) of each of the given reactions are to be determined.

Concept Introduction:

1-fluoro-2,4-dinitrobenzene is used to protect the anime group of an amino acid.

Hydrolysis of a peptide with a 1-fluoro-2,4-dinitrobenzene protected N terminus results in hydrolysis of amide bonds in the peptide.

Treatment of a peptide with phenyl isothiocyanate protects the N terminus of the chain. Subsequent treatment with a strong acid in anhydrous conditions cleaves only the amide bond between the protected amino acid residue and the rest of the peptide chain.

Benzyloxycarbonyl chloride is used to protect the amine group of an amino acid.

N,N'-dicyclohexylcarbodiimide is used as a dehydrating agent in peptide and ester formation reactions.

Hydrogenolysis with hydrogen over palladium is used for deprotection of N terminus.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26, Problem 38P

Interpretation Introduction

Interpretation:

The product(s) of each of the given reactions are to be determined.

Concept Introduction:

1-fluoro-2,4-dinitrobenzene is used to protect the anime group of an amino acid.

Hydrolysis of a peptide with a 1-fluoro-2,4-dinitrobenzene protected N terminus results in hydrolysis of amide bonds in the peptide.

Treatment of a peptide with phenyl isothiocyanate protects the N terminus of the chain. Subsequent treatment with a strong acid in anhydrous conditions cleaves only the amide bond between the protected amino acid residue and the rest of the peptide chain.

Benzyloxycarbonyl chloride is used to protect the amine group of an amino acid.

N,N'-dicyclohexylcarbodiimide is used as a dehydrating agent in peptide and ester formation reactions.

Hydrogenolysis with hydrogen over palladium is used for deprotection of N terminus.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 26, Problem 38P

Interpretation Introduction