Organic Chemistry
7th Edition
ISBN: 9780321803221
Author: Paula Y. Bruice
Publisher: Prentice Hall
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Chapter 26, Problem 39P
Staphylococcus nuclease is an enzyme that catalyzes the hydrolysis of DNA.
The reaction is catalyzed by Ca2+, Glu 43, and Arg 87. Propose a mechanism for this reaction. Recall that the
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3. Propose a synthesis for the following transformation. Do not draw an arrow-pushing
mechanism below, but make sure to draw the product of each proposed step (3 points).
CN
+ En
CN
3) Propagation of uncertainty. Every measurement has uncertainty. In this problem, we'll
evaluate the uncertainty in every step of a titration of potassium hydrogen phthalate (a
common acid used in titrations, abbreviated KHP, formula CsH5KO4) with NaOH of an
unknown concentration.
The calculation that ultimately needs to be carried out is:
concentration NaOH
1000 x mass KHP × purity KHP
molar mass KHP x volume NaOH
Measurements:
a) You use a balance to weigh 0.3992 g of KHP. The uncertainty is ±0.15 mg (0.00015
g).
b) You use a buret to slowly add NaOH to the KHP until it reaches the endpoint. It takes
18.73 mL of NaOH. The uncertainty of the burst is 0.03 mL..
c) The manufacturer states the purity of KHP is 100%±0.05%.
d) Even though we don't think much about them, molar masses have uncertainty as well.
The uncertainty comes from the distribution of isotopes, rather than random
measurement error. The uncertainty in the elements composing KHP are:
a. Carbon:
b. Hydrogen:
±0.0008…
Don't used hand raiting and don't used Ai solution
Chapter 26 Solutions
Organic Chemistry
Ch. 26.1 - In acidic solutions, nucleosides are hydrolyzed to...Ch. 26.1 - Draw the structure for each of the following: a....Ch. 26.2 - Prob. 3PCh. 26.3 - Indicate whether each functional group of the five...Ch. 26.3 - Prob. 5PCh. 26.3 - If one of the strands of DNA has the following...Ch. 26.4 - The 2',3-cyclic phosphodiester that is formed...Ch. 26.5 - Using a dark line for the original parental DNA...Ch. 26.7 - Why do both thymine and uracil specify the...Ch. 26.9 - If methionine is always the first amino acid...
Ch. 26.9 - Four Cs occur in a row in the segment of mRNA...Ch. 26.9 - UAA is a stop codon. Why does the UAA sequence in...Ch. 26.9 - Prob. 13PCh. 26.9 - Write the sequences of bases in the sense strand...Ch. 26.9 - List the possible codons on mRNA that speciy each...Ch. 26.10 - Adenine can be deaminated to hypoxanthine, and...Ch. 26.10 - Explain why thymine cannot be deaminated.Ch. 26.12 - Which of the following base sequences is most...Ch. 26 - Name the following:Ch. 26 - What nonapeptide is coded for by the following...Ch. 26 - What is the sequence of bases in the template...Ch. 26 - Prob. 22PCh. 26 - Prob. 23PCh. 26 - Prob. 24PCh. 26 - Propose a mechanism for the following reaction:Ch. 26 - A segment of DNA has 18 base pairs. It has 7...Ch. 26 - Match the codon with the anticodon:Ch. 26 - Prob. 28PCh. 26 - Which of the following pairs of dinucleotides are...Ch. 26 - Human immunodeficiency virus (HIV) is the...Ch. 26 - If a mRNA contained only U and G in random...Ch. 26 - Why is the codon a triplet rather than a doublet...Ch. 26 - RNAase, the enzyme that catalyzes the hydrolysis...Ch. 26 - The amino acid sequences of peptide fragments...Ch. 26 - Which cytosine in the following sense strand of...Ch. 26 - Prob. 36PCh. 26 - Sodium nitrite, a common food preservative (page...Ch. 26 - Why does DNA not unravel completely before...Ch. 26 - Staphylococcus nuclease is an enzyme that...Ch. 26 - The first amino acid incorporated into a...
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