Microbiology: An Introduction
Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 26, Problem 2CAE

A 28-year-old woman was admitted to a Wisconsin hospital with a 1-week history of arthritis of the left knee. Four days later, a 32-year-old man was examined for a 2-week history of urethritis and a swollen, painful left wrist. A 20-year-old woman seen in a Philadelphia hospital had pain in the right knee, left ankle, and left wrist for 3 days. Pathogens cultured from synovial fluid or urethral culture were gram-negative diplococci that required proline to grow. Antibiotic sensitivity tests gave the following results:

Antibiotic MIC Tested (μg/ml)

Susceptible MIC (μg/ml)
Cefoxitin 0.5   ≤2
Penicillin 8   ≤0.06
Spectinomycin 64   ≤32
Tetracycline 4   ≤0.25

What is the pathogen, and how is this disease transmitted? Which of the antibiotics should be used for treatment? What is the evidence that these cases are related?

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Gram positive case   on the first day back to class at the local university, a student noticed a small abscess on his right elbow but didn't think much about it. Over the next couple days, however the abscess became more swollen and painful. The student decided to visit the health centet he told the doctor it looked like a spider bite but didn't recall being bitten. The doctor took a swab of the lesion and prescribed an antibiotic cream as it looked infected. The swab was sent to the lab for testing within a few days of treatment, the student lesion was healed.       What is the overview of the disease? How did the patient most likely acquire it? How else does this organism spread to cause this disease?
Gram positive case   on the first day back to class at the local university, a student noticed a small abscess on his right elbow but didn't think much about it. Over the next couple days, however the abscess became more swollen and painful. The student decided to visit the health centet he told the doctor it looked like a spider bite but didn't recall being bitten. The doctor took a swab of the lesion and prescribed an antibiotic cream as it looked infected. The swab was sent to the lab for testing within a few days of treatment, the student lesion was healed.   answer the questions:   plate morphology: gram stain: catalase: coagulase: bactracin: TSI
Gram positive case   on the first day back to class at the local university, a student noticed a small abscess on his right elbow but didn't think much about it. Over the next couple days, however the abscess became more swollen and painful. The student decided to visit the health centet he told the doctor it looked like a spider bite but didn't recall being bitten. The doctor took a swab of the lesion and prescribed an antibiotic cream as it looked infected. The swab was sent to the lab for testing within a few days of treatment, the student lesion was healed.   Answer questions:    plate morphology: (example: SBR agar-small, translucent, round colonies showing beta hemolysis)    gram stain:  catalase: caugulase:    bactiracin:    TSI:

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