Organic Chemistry
2nd Edition
ISBN: 9781118452288
Author: David R. Klein
Publisher: WILEY
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Question
Chapter 2.6, Problem 20CC
(a)
Interpretation Introduction
Interpretation:
The most likely pharmacophore has to be identified.
Concept Introduction:
The part of each compound that is responsible for the analgesic activity is called as pharmacophore. If a part of pharmacophore is detached or distorted, the resulting compound would not have the capacity to bind effectively to the biological receptor, and the compound doesn’t show any analgesic properties.
(b)
Interpretation Introduction
Interpretation:
The most likely pharmacophore has to be identified.
Concept Introduction:
The part of each compound that is responsible for the analgesic activity is called as pharmacophore. If a part of pharmacophore is detached or distorted, the resulting compound would not have the capacity to bind effectively to the biological receptor, and the compound doesn’t show any analgesic properties.
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34. Give the expected major product of each of the following reactions.
Conc. HI
a. CH3CH2CH2OH
b. (CH3)2CHCH2CH2OH
Conc. HBr
H
Conc. HI
C.
OH
Conc.HCI
d. (CH3CH2)3COH
42. Which of the following halogenated compounds can be used successfully to prepare a Grignard reagent for
alcohol synthesis by subsequent reaction with an aldehyde or ketone? Which ones cannot and why?
H3C CH3
a.
Br
H OH
b.
Cl
C.
I H
H
d. Cl
e.
H
OCH3
Br
H
For each reaction below, decide if the first stable organic product that forms in solution will create a new CC bond, and check
the appropriate box.
Next, for each reaction to which you answered "Yes" to in the table, draw this product in the drawing area below.
Note for advanced students: for this problem, don't worry if you think this product will continue to react under the current conditions
- just focus on the first stable product you expect to form in solution.
?
Will the first
MgBr
product that forms in this reaction
create a new CC bond?
olo
?
OH
جمله
O Yes
Ⓒ No
MgCl
?
Will the first product that forms in this reaction
create a new CC bond?
Click and drag to start drawing a
structure.
Yes
No
X
☐ :
☐
टे
PH
Chapter 2 Solutions
Organic Chemistry
Ch. 2.1 - Prob. 1LTSCh. 2.1 - Prob. 1PTSCh. 2.1 - Prob. 2ATSCh. 2.1 - Prob. 3ATSCh. 2.1 - Prob. 4ATSCh. 2.2 - Prob. 2LTSCh. 2.2 - Prob. 5PTSCh. 2.2 - Prob. 6ATSCh. 2.2 - Prob. 7ATSCh. 2.2 - Prob. 3LTS
Ch. 2.2 - Prob. 8PTSCh. 2.2 - Prob. 9ATSCh. 2.2 - Prob. 10ATSCh. 2.3 - Prob. 11CCCh. 2.4 - Prob. 12CCCh. 2.4 - Prob. 13CCCh. 2.5 - Prob. 4LTSCh. 2.5 - Prob. 14PTSCh. 2.5 - Prob. 15ATSCh. 2.5 - Prob. 5LTSCh. 2.5 - Prob. 16PTSCh. 2.5 - Prob. 17ATSCh. 2.5 - Prob. 18ATSCh. 2.5 - Prob. 19ATSCh. 2.6 - Prob. 20CCCh. 2.8 - Prob. 6LTSCh. 2.8 - Prob. 21PTSCh. 2.8 - Prob. 22ATSCh. 2.9 - Prob. 7LTSCh. 2.9 - Prob. 23PTSCh. 2.9 - Prob. 24ATSCh. 2.10 - Prob. 25CCCh. 2.10 - Prob. 26CCCh. 2.10 - Prob. 27CCCh. 2.10 - Prob. 28CCCh. 2.10 - Prob. 29CCCh. 2.10 - Prob. 30CCCh. 2.10 - Prob. 31CCCh. 2.10 - Prob. 32CCCh. 2.11 - Prob. 8LTSCh. 2.11 - Prob. 33PTSCh. 2.11 - Prob. 34ATSCh. 2.11 - Prob. 35ATSCh. 2.12 - Prob. 9LTSCh. 2.12 - Prob. 36PTSCh. 2.12 - Prob. 37ATSCh. 2.12 - Prob. 38ATSCh. 2 - Prob. 39PPCh. 2 - Prob. 40PPCh. 2 - Prob. 41PPCh. 2 - Prob. 42PPCh. 2 - Prob. 43PPCh. 2 - Prob. 44PPCh. 2 - Prob. 45PPCh. 2 - Prob. 46PPCh. 2 - Prob. 47PPCh. 2 - Prob. 48PPCh. 2 - Prob. 49PPCh. 2 - Prob. 50PPCh. 2 - Prob. 51PPCh. 2 - Prob. 52PPCh. 2 - Prob. 53PPCh. 2 - Prob. 54PPCh. 2 - Prob. 55PPCh. 2 - Prob. 56PPCh. 2 - Prob. 57PPCh. 2 - Prob. 58PPCh. 2 - Prob. 59PPCh. 2 - Prob. 60PPCh. 2 - Prob. 61PPCh. 2 - Prob. 62PPCh. 2 - Prob. 65IPCh. 2 - Prob. 66IPCh. 2 - Prob. 67IP
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