Microbiology: An Evolving Science (Fourth Edition)
Microbiology: An Evolving Science (Fourth Edition)
4th Edition
ISBN: 9780393615098
Author: John W. Foster, Joan L. Slonczewski
Publisher: W. W. Norton & Company
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Chapter 25.6, Problem 4TQ
Summary Introduction

To review:

The strategies which can be used for delivering E3 ligase enzyme into the host cell infected with Listeria monocytogens.

Introduction:

The ubiquitin ligase enzyme, also known as E3 ubiquitin ligase, is a protein involved in the ubiquitiylation of target proteins. It recruits an E2 ubiquitin-conjugating enzyme that is loaded with ubiquitin and catalyzes the transfer of ubiquitin to the protein substrate. It specifically links ubiquitin with the lysine residue of target protein through an isopeptide bond.

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