Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified. Concept introduction: Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as, Steps involved in Strecker synthesis are, Protonation of carbonyl Nucleophilic attack of ammonia to form imine Attack of cyanide to form α -aminonitrile Hydrolysis to give α -aminoacid To find : the reagents used for synthesis of methionine by Strecker synthesis.

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Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

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Answer 2

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Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 5

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

Answer 6

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

Answer 7

Chapter 25.3, Problem 17CC

(a)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of methionine by Strecker synthesis.

Answer 8

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

Answer 9

(b)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of histidine by Strecker synthesis.

Answer 10

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

Answer 11

(c)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of phenylalanine by Strecker synthesis.

Answer 12

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

Answer 13

d)

Interpretation Introduction

Interpretation:

Reagents required for preparation of methionine, histidine, phenylalanine and leucine by using Strecker synthesis need to be identified.

Concept introduction:

Strecker synthesis is a process in which the aldehyde reacts with ammonium chloride and alkali cyanide to form α -aminonitrile. The formed α -aminonitrile is undergoes hydrolysis to give the respective amino acids. The general scheme can be shown as,

Steps involved in Strecker synthesis are,

Protonation of carbonyl

Nucleophilic attack of ammonia to form imine

Attack of cyanide to form α -aminonitrile

Hydrolysis to give α -aminoacid

To find: the reagents used for synthesis of leucine by Strecker synthesis.

Answer 14

Expert Solution & Answer

Answer 15

Expert Solution & Answer

Answer 16

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Answer 17

Ch. 25.2 - Prob. 1CC Ch. 25.2 - Prob. 2CC Ch. 25.2 - Prob. 3CC Ch. 25.2 - Prob. 1LTS Ch. 25.2 - Prob. 4PTS Ch. 25.2 - Prob. 7CC Ch. 25.2 - Prob. 8CC Ch. 25.2 - Prob. 9CC Ch. 25.2 - Prob. 10CC Ch. 25.2 - Prob. 11CC

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Chapter 25 Solutions