ORGANIC CHEMISTRY-PRINT (LL)-W/WILEY
ORGANIC CHEMISTRY-PRINT (LL)-W/WILEY
4th Edition
ISBN: 9781119761105
Author: Klein
Publisher: WILEY
Question
Book Icon
Chapter 25, Problem 51PP

(a)

Interpretation Introduction

Interpretation:

The form of amino acid that predominates are the isoelectric point need to be identified.

Concept introduction:

Amino acids at a particular pH do not migrate in an electric field.  This pH is known as the isoelectric point.  The isoelectric point is also known as isoionic point.  At this isoelectric point the amino acid is neutral.  This means that the zwitterion form predominates more over the other forms.  pI is the isoelectric point and this can be given by average of the pKa.

pI=pKa1+pKa22

The carboxylic acid form will predominate if, pI<pKa and carboxylate form will predominate if, pI>pKa .

The uncharged amino form will predominate if, pI>pKa and the protonated amino form will predominate if, pI<pKa .

For the side chain the same rule applies as of for carboxylic acid and amino group.

(b)

Interpretation Introduction

Interpretation:

The form of amino acid that predominates are the isoelectric point need to be identified.

Concept introduction:

Amino acids at a particular pH do not migrate in an electric field.  This pH is known as the isoelectric point.  The isoelectric point is also known as isoionic point.  At this isoelectric point the amino acid is neutral.  This means that the zwitterion form predominates more over the other forms.  pI is the isoelectric point and this can be given by average of the pKa.

pI=pKa1+pKa22

The carboxylic acid form will predominate if, pI<pKa and carboxylate form will predominate if, pI>pKa .

The uncharged amino form will predominate if, pI>pKa and the protonated amino form will predominate if, pI<pKa .

For the side chain the same rule applies as of for carboxylic acid and amino group.

(c)

Interpretation Introduction

Interpretation:

The form of amino acid that predominates are the isoelectric point need to be identified.

Concept introduction:

Amino acids at a particular pH do not migrate in an electric field.  This pH is known as the isoelectric point.  The isoelectric point is also known as isoionic point.  At this isoelectric point the amino acid is neutral.  This means that the zwitterion form predominates more over the other forms.  pI is the isoelectric point and this can be given by average of the pKa.

pI=pKa1+pKa22

The carboxylic acid form will predominate if, pI<pKa and carboxylate form will predominate if, pI>pKa .

The uncharged amino form will predominate if, pI>pKa and the protonated amino form will predominate if, pI<pKa .

For the side chain the same rule applies as of for carboxylic acid and amino group.

(d)

Interpretation Introduction

Interpretation:

The form of amino acid that predominates are the isoelectric point need to be identified.

Concept introduction:

Amino acids at a particular pH do not migrate in an electric field.  This pH is known as the isoelectric point.  The isoelectric point is also known as isoionic point.  At this isoelectric point the amino acid is neutral.  This means that the zwitterion form predominates more over the other forms.  pI is the isoelectric point and this can be given by average of the pKa.

pI=pKa1+pKa22

The carboxylic acid form will predominate if, pI<pKa and carboxylate form will predominate if, pI>pKa .

The uncharged amino form will predominate if, pI>pKa and the protonated amino form will predominate if, pI<pKa .

For the side chain the same rule applies as of for carboxylic acid and amino group.

Blurred answer
Students have asked these similar questions
Using wedge-and-dash bonds, modify the bonds on the chiral carbon in the molecule below so the molecule has R stereochemical configuration. NH H Br X टे
Provide photos of models of the following molecules. (Include a key for identification of the atoms) 1,2-dichloropropane 2,3,3-trimethylhexane 2-bromo-3-methybutane
Please draw the structure in the box that is consistent with all the spectral data and alphabetically label all of the equivalent protons in the structure (Ha, Hb, Hc....) in order to assign all the proton NMR peaks. The integrations are computer generated and approximate the number of equivalent protons. Molecular formula: C13H1802 14 13 12 11 10 11 (ppm) Structure with assigned H peaks 2.08 3.13

Chapter 25 Solutions

ORGANIC CHEMISTRY-PRINT (LL)-W/WILEY

Knowledge Booster
Background pattern image
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Chemistry
Chemistry
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Cengage Learning
Text book image
Chemistry
Chemistry
ISBN:9781259911156
Author:Raymond Chang Dr., Jason Overby Professor
Publisher:McGraw-Hill Education
Text book image
Principles of Instrumental Analysis
Chemistry
ISBN:9781305577213
Author:Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:Cengage Learning
Text book image
Organic Chemistry
Chemistry
ISBN:9780078021558
Author:Janice Gorzynski Smith Dr.
Publisher:McGraw-Hill Education
Text book image
Chemistry: Principles and Reactions
Chemistry
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:Cengage Learning
Text book image
Elementary Principles of Chemical Processes, Bind...
Chemistry
ISBN:9781118431221
Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:WILEY