MICROBIOLOGY: EVOLV.SCI.-W/ACCESS>CI<
4th Edition
ISBN: 9780393622805
Author: SLONCZEWSKI
Publisher: Norton custom
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Chapter 24, Problem 2TQ
Summary Introduction
To review:
The working of an immune system against different pathogens like poliovirus and Staphylococcus aureus.
Introduction:
A vaccine is comprised of the inactive or harmless form of bacteria or pathogen that may cause disease in human beings. The vaccines can be injected directly or can be given orally to an individual. The vaccine enables the immune system of the body to get prepared for that pathogenic invasion in the future.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Chapter 24 Solutions
MICROBIOLOGY: EVOLV.SCI.-W/ACCESS>CI<
Ch. 24.1 - Prob. 1TQCh. 24.1 - Prob. 2TQCh. 24.1 - Prob. 3TQCh. 24.2 - Prob. 1TQCh. 24.2 - Prob. 2TQCh. 24.2 - Prob. 3TQCh. 24.2 - Prob. 4TQCh. 24.2 - Prob. 5TQCh. 24.3 - Prob. 1TQCh. 24.3 - Prob. 2TQ
Ch. 24.3 - Prob. 3TQCh. 24.4 - Prob. 1TQCh. 24.4 - Prob. 2TQCh. 24.5 - Prob. 1TQCh. 24.5 - Prob. 2TQCh. 24.6 - Prob. 1TQCh. 24.6 - Prob. 2TQCh. 24 - Prob. 1RQCh. 24 - Prob. 2RQCh. 24 - Prob. 3RQCh. 24 - Prob. 4RQCh. 24 - Prob. 5RQCh. 24 - Prob. 6RQCh. 24 - Prob. 7RQCh. 24 - Prob. 8RQCh. 24 - Prob. 9RQCh. 24 - Prob. 10RQCh. 24 - Prob. 11RQCh. 24 - Prob. 12RQCh. 24 - Prob. 13RQCh. 24 - Prob. 14RQCh. 24 - Prob. 15RQCh. 24 - Prob. 16RQCh. 24 - Prob. 17RQCh. 24 - Prob. 18RQCh. 24 - Prob. 19RQCh. 24 - Prob. 20RQCh. 24 - Prob. 1TQCh. 24 - Prob. 2TQCh. 24 - Prob. 3TQCh. 24 - Prob. 4TQCh. 24 - Prob. 5TQ
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