Interpretation: The bicyclic ring systems among the given systems that can be prepared by an intermolecular Robinson annulation are to be stated.
Concept Introduction: The combination of the Michael reaction and intramolecular aldol reaction in which the formation of a ring takes place is known as Robinson annulation reaction. In this reaction, the carbonyl compound is treated with a base which leads to the elimination of a proton from the
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ORGANIC CHEMISTRY
- Classify the following reactions.arrow_forwardPlease fill in the missing reactants, reagents or products in the following reactions. Indicate relative stereochemistry where it is necessary CI j)arrow_forwardWhich of the following statements best describes the general reactivity of alkynes? O An alkyne reacts as an electrophile and is therefore electron poor. O An alkyne reacts as an electrophile and is therefore electron rich. O An alkyne reacts as a nucleophile and is therefore electron poor. O An alkyne reacts as a nucleophile and is therefore electron rich. O Alkynes fail to undergo electrophilic addition reactions, unlike alkenes.arrow_forward
- Consider this scheme. Why does a ring form with a single ethylene glycol on A rather than two molecules of ethylene glycol to form acyclic acetals? Intramolecular reactions are A unfavorable when compared to intermolecular reactions Acyclic molecules are unfavorable compared to rings В in all cases The change in entropy is favorable for ring formation and strain is low in a five- membered ring Sterics prevents acyclic molecules from forming in this D case H HCI + HOCH2CH2OH H + H2Oarrow_forwardwhat is the structure of the substitution product in the following reaction and consider stereochemistry in deciding your product?arrow_forwardWhat is the correct classification of the following pericyclic reaction? electrophilic addition sigmatropic rearrangement cycloaddition electrocyclic reaction Onucleophilic substitutionarrow_forward
- 22:43 10. Provide the following: the resonance structure of the intermediate that can resonate into the other intermediate that is given the product that results from the given resonance structure Specify which product is the kinetic product and which is the thermodynamic product . OH 50% H₂SO4 H~arrow_forwardWhich of the following compounds can be prepared by intramolecular Robinson annulation? A B Carrow_forwardGenerally, addition of halogen acids to alkene follows Markovnikov rule. In which condition the anti-Markovnikov rule is followed? Describe the mechanism with an example.arrow_forward
- Predict the stereochemistry For the E2 reaction Draw a Newmann Projection of the reactive con Formation and the Structure For only major product of the reaction. Brarrow_forwardDescribe Suprafacial and Antarafacial Rearrangement:arrow_forwardDraw the major organic product(s) of the following reactions including stereochemistry when it is appropriate. -CH₂-CEC-H H₂O/H₂SO4 /HgOarrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning