Chapter 24, Problem 24.23P

Interpretation Introduction

Interpretation:

Reagents and the other fragment used to carry out the indicated conversion have to be suggested.

Concept Introduction:

Suzuki coupling uses a boron reagent $R^{\text{'}}-B{Y}_2$ with an alkenyl, aryl, or alkynyl halide or triflate with a palladium salt to give new C-C bond.

The boron compound used is borane ($R^{\text{'}}{}_{3}B$), borate ester ${\text{R}}^{\text{'}}{}_{\text{3}}{\text{-B(OR}}_{\text{2}}\text{)}$ or boric acid ${\text{R}}^{\text{'}}{}_{\text{3}}{\text{-B(OH}}_{\text{2}}\text{)}$, where R can be alkyl, alkenyl, or aryl group.

Suzuki coupling Reaction:

  $\text{RX}\text{+}{\text{R}}^{\text{'}}{}_{\text{3}}{\text{-BY}}_{\text{2}}\stackrel{\begin{array}{l}Pd{L}_4\\ Base\end{array}}{\to }R-R^{\text{'}}+XB{Y}_2$