ANATOMY+PHYSIOLOGY >LOOSE<
8th Edition
ISBN: 9781308329826
Author: SALADIN
Publisher: MCG/CREATE
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Chapter 23.4, Problem 3AYLO
Summary Introduction
To discuss:
How the PCT reabsorbs NaCl, other electrolytes, glucose, urea, and water; why the reabsorption of water and solutes depends directly or indirectly on the sodium-glucose transporter (SGLT) and sodium reabsorption.
Introduction:
In the whole of the glomerular filtrate, about 65% are reabsorbed by the proximal convoluted tubule. The proximal convoluted tubule removes wastes present in the blood and excretes them through the urine. Due to the presence of microvilli (its greater length), the proximal convoluted tubule has the benefits of increasing its surface area for absorption. Proximal convoluted tubule cells are equipped with a rich source of large mitochondria that produce ATP, which supports active transport. Of all the calories that are consumed in a day, only 6% of ATP is needed by the proximal convoluted tubule.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Zero-Order Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Chapter 23 Solutions
ANATOMY+PHYSIOLOGY >LOOSE<
Ch. 23.1 - State at least four functions of the kidneys other...Ch. 23.1 - Prob. 2BYGOCh. 23.1 - Prob. 3BYGOCh. 23.1 - Prob. 1AYLOCh. 23.1 - Prob. 2AYLOCh. 23.1 - Prob. 3AYLOCh. 23.1 - Blood urea nitrogen, azotemia, and uremia, and the...Ch. 23.1 - Prob. 5AYLOCh. 23.2 - Prob. 4BYGOCh. 23.2 - Prob. 5BYGO
Ch. 23.2 - Prob. 6BYGOCh. 23.2 - Prob. 1AYLOCh. 23.2 - Prob. 2AYLOCh. 23.2 - Three layers of tissue that surround and...Ch. 23.2 - Prob. 4AYLOCh. 23.2 - Prob. 5AYLOCh. 23.2 - Prob. 6AYLOCh. 23.2 - Prob. 7AYLOCh. 23.2 - Prob. 8AYLOCh. 23.2 - Prob. 9AYLOCh. 23.2 - Prob. 10AYLOCh. 23.2 - Prob. 11AYLOCh. 23.2 - Prob. 12AYLOCh. 23.3 - Prob. 7BYGOCh. 23.3 - Prob. 8BYGOCh. 23.3 - Prob. 9BYGOCh. 23.3 - Prob. 10BYGOCh. 23.3 - Prob. 1AYLOCh. 23.3 - Prob. 2AYLOCh. 23.3 - Prob. 3AYLOCh. 23.3 - Prob. 4AYLOCh. 23.3 - Prob. 5AYLOCh. 23.3 - Prob. 6AYLOCh. 23.3 - How the myogenic mechanism of renal autoregulation...Ch. 23.3 - Structure and function of the juxtaglomerular...Ch. 23.3 - Prob. 9AYLOCh. 23.3 - Prob. 10AYLOCh. 23.3 - Prob. 11AYLOCh. 23.4 - Prob. 1AYLOCh. 23.4 - Prob. 2AYLOCh. 23.4 - Prob. 3AYLOCh. 23.4 - Prob. 4AYLOCh. 23.4 - Prob. 5AYLOCh. 23.4 - Prob. 6AYLOCh. 23.4 - Prob. 7AYLOCh. 23.4 - The reabsorption of water, Cl-, and glucose by the...Ch. 23.4 - Prob. 12BYGOCh. 23.4 - Prob. 13BYGOCh. 23.5 - Prob. 1AYLOCh. 23.5 - Prob. 2AYLOCh. 23.5 - Prob. 3AYLOCh. 23.5 - Function of the countercurrent multiplier and how...Ch. 23.5 - Prob. 5AYLOCh. 23.5 - Prob. 14BYGOCh. 23.5 - Prob. 15BYGOCh. 23.5 - Prob. 16BYGOCh. 23.6 - Prob. 1AYLOCh. 23.6 - Prob. 2AYLOCh. 23.6 - Prob. 3AYLOCh. 23.6 - Prob. 4AYLOCh. 23.6 - Prob. 5AYLOCh. 23.6 - Prob. 6AYLOCh. 23.6 - Prob. 7AYLOCh. 23.6 - Prob. 8AYLOCh. 23.6 - Prob. 17BYGOCh. 23.6 - Prob. 18BYGOCh. 23.6 - Prob. 19BYGOCh. 23.6 - Prob. 20BYGOCh. 23.7 - Prob. 21BYGOCh. 23.7 - Prob. 22BYGOCh. 23.7 - Prob. 23BYGOCh. 23.7 - The route and mechanism of urine transport from...Ch. 23.7 - Prob. 2AYLOCh. 23.7 - Prob. 3AYLOCh. 23.7 - Anatomy of the male urethra, its three segments,...Ch. 23.7 - The mechanism of the spinal micturition reflex and...Ch. 23.7 - Prob. 6AYLOCh. 23 - Beavers have relatively little need to conserve...Ch. 23 - Prob. 10TYRCh. 23 - Prob. 11TYRCh. 23 - _______ is the ability of a nephron to adjust its...Ch. 23 - The two ureters and the urethra form the...Ch. 23 - The _______ is a group of epithelial cells of the...Ch. 23 - To enter the capsular space, filtrate must pass...Ch. 23 - Glycosuria occurs if the rate of glomerular...Ch. 23 - Prob. 17TYRCh. 23 - Prob. 18TYRCh. 23 - Prob. 19TYRCh. 23 - Prob. 20TYRCh. 23 - Prob. 8BYMVCh. 23 - pyelo-Ch. 23 - Prob. 10BYMVCh. 23 - Prob. 6WWTSCh. 23 - Prob. 7WWTSCh. 23 - The minimum osmolarity of urine is 300 mOsm/L,...Ch. 23 - Prob. 9WWTSCh. 23 - Prob. 10WWTSCh. 23 - Prob. 1BYMVCh. 23 - Prob. 2BYMVCh. 23 - Prob. 3BYMVCh. 23 - Prob. 4BYMVCh. 23 - Prob. 5BYMVCh. 23 - Prob. 6BYMVCh. 23 - Prob. 7BYMVCh. 23 - Prob. 1TYRCh. 23 - The compact ball of capillaries in a nephron is...Ch. 23 - Prob. 3TYRCh. 23 - Prob. 4TYRCh. 23 - Most sodium is reabsorbed from the glomerular...Ch. 23 - Prob. 6TYRCh. 23 - Prob. 7TYRCh. 23 - Prob. 8TYRCh. 23 - Prob. 1WWTSCh. 23 - Prob. 2WWTSCh. 23 - Prob. 3WWTSCh. 23 - Tight junctions prevent material from leaking...Ch. 23 - Prob. 5WWTSCh. 23 - Prob. 1TYCCh. 23 - Prob. 2TYCCh. 23 - Prob. 3TYCCh. 23 - Drugs called renin inhibitors are used to treat...Ch. 23 - Prob. 5TYC
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