Campbell Biology (11th Edition)
11th Edition
ISBN: 9780134093413
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Chapter 23.3, Problem 2CC
Distinguish genetic draft from gene flow in terms of (a) how they occur and (b) their irnplications for future
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Distinguish genetic drift from gene flow in terms of(a) how they occur and (b) their implications for futuregenetic variation in a population.
1a) Define the term linkage disequilibrium.
(b) Explain why it makes sense that natural selection can maintain linkage disequilibrium between two loci that are not physically linked when there is epistasis for fitness.
(c) Explain the role of linkage disequilibrium in employing QTL mapping as a way to investigate the genetic architecture of adaptive traits.
The use of nucleotide sequence data to measure genetic variability is complicated by the fact that the genes of higher eukaryotes are complex in organization and contain 5′ and 3′ flanking regions as well as introns. Researchers have compared the nucleotide sequence of two cloned alleles of the g-globin gene from a single individual and found a variation of 1 percent. Those differences include 13 substitutions of one nucleotide for another and 3 short DNA segments that have been inserted in one allele or deleted in the other. None of the changes takes place in the gene’s exons (coding regions). Why do you think this is so, and should it change our concept of genetic variation?
Chapter 23 Solutions
Campbell Biology (11th Edition)
Ch. 23.1 - Explain why genetic Variation within a population...Ch. 23.1 - Ot all the mutations that occur in a population,...Ch. 23.1 - MAKE CONNECTIONS If a population stopped...Ch. 23.2 - A population has 700 individuals, 85 of genotype...Ch. 23.2 - The frequency of allele a is 0.45 for a population...Ch. 23.2 - WHAT IF? A locus that affects susceptibility to a...Ch. 23.3 - In what sense is natural selection more...Ch. 23.3 - Distinguish genetic draft from gene flow in terms...Ch. 23.3 - WH AT IF? Suppose two plant populations exchange...Ch. 23.4 - What is the relative fitness of a sterile mule?...
Ch. 23.4 - Explain why natural selection is the only...Ch. 23.4 - Prob. 3CCCh. 23 - Typically. most of the nucleotide variabillity...Ch. 23 - Is it circular reasoning to calculate p ond q from...Ch. 23 - Would two small, geographically isolated...Ch. 23 - How might secondary sex characteristics in males...Ch. 23 - Natural selection changes allele frequencies...Ch. 23 - Prob. 2TYUCh. 23 - Prob. 3TYUCh. 23 - There are 25 individuals in population 1, all with...Ch. 23 - Prob. 5TYUCh. 23 - EVOLUTION CONNECTION Using at least two examples,...Ch. 23 - SCIENTIFIC INQUIRY INTERPRET THE DATA Researchers...Ch. 23 - Prob. 8TYUCh. 23 - SYNTHESI2E YOUR KNOWLEDGE This kettle lake forracd...
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- What are considered significant factors in maintaining the surprisinglyhigh levels of genetic variation in natural populations ?arrow_forwardThe Human Genome Project has demonstrated that in humans of all races and nationalities approximately 99.9 percent of the sequence is the same, yet different individuals can be identified by DNA fingerprinting techniques. What is one primary variation in the human genome that can be used to distinguish different individuals? Briefly explain your answer.arrow_forwardGive typing answer with explanation and conclusion If you want to identify genes linked to autism in a mouse model, which genetic approach or approaches could you use? (Mark all that apply) A) Reverse Genetics B) Forward Genetics C) Optogenetics D) Population Geneticsarrow_forward
- 1a) In a very large population, if the forward and reverse mutation rates are exactly the same, how would you expect the frequency of an original, non-mutated allele to change in the population over time? Will the population eventually achieve an equilibrium value of the frequency of the non-mutated allele? b) What if the forward mutation rate is one order of magnitude larger (e. 10X) than the reverse mutation rate? Do you expect the frequency of the original, non-mutated allele to increase, decrease, or stay the same over time? c) If the population size is considerably smaller, does this change your expectations for changes in the frequency of the original, non-mutated allele over several generations?arrow_forwardSteven Frank and Laurence Hurst argued that a cytoplasmically inherited mutation in humans that has severe effects in males but no effect in females will not be eliminated from a population by natural selection because only females pass on mtDNA (S. A. Frank and L. D. Hurst. 1996. Nature 383:224). Using this argument, explain why males with Leber hereditary optic neuropathy are more severely affected than females.arrow_forwardThe agouti gene determines coat colour in mice. Heterozygous mice have yellow coats, while homozygous dominant mice have black coats. However, having two copies of the recessive alleles is lethal. In a population of 2 000 mice, 1 082 mice have black coats. a) Calculate the frequency of each allele. Show all your work and express your answer as a value between 0 and 1 rounded to two decimal places. b) What percentage of the mouse population is expected to be carriers of the lethal allele? Show all your work and express your answer rounded to one decimal place. c) How many mice will die during fetal development? Show all your work and round your answer to the closest whole number.arrow_forward
- Asthma is a common medical condition that is influenced by genetics and environment. In the US, appraximately 9% of adults have asthma. A recent genome wide association study (GWAS) identifieda genetic variation that increases asthma risk by S0% when a single copy of the risk variant is present in a genome. Which value below would represent the approximate asthma risk of an individual with this genetic variation in their genome? Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a 59% b 50% 14.5% 9.5% e 9%arrow_forwardDescribe autotrophy and heterotrophy and provide a few examples of each that illustrate the diversity of how organisms obtain energy. What trade-offs are associated with the heterotrophic consumption of live animals versus dead plant materials? Why is the mutation critical to the formation of new alleles and central to the evolutionary process? Give examples and explain in terms of allele frequency changearrow_forwarda.) If all the blue dots represent FST values between one species in the Americas and one species in Oceania, does this pattern of genetic similarity on the graph suggest that Native Americans and the people of Oceania followed very different migration routes? Why or why not? b.) Given the maximum possible FST value (based on how this statistic is calculated), is it feasible that all human populations have most of the genetic variation within a given population with very little genetic differentiation between any two populations? Give a reason for your answer. c.) Does the graph above suggest that interbreeding during these human contacts had a considerable effect on the gene pools of the two communities? Or is it more likely that only very limited or no interbreeding took place between islanders of Oceania and Native Americans from S. America? Give a reason for your answer.arrow_forward
- a) Name and define the evolutionary processes that cause change in allele frequencies acrossgenerations. b) Describe how each process is expected to change allele frequencies across generations,including the following terms as appropriate:- genome-wide effects, loci-specific effects advantageous, deleterious, neutral- population size- speed of evolutionary changearrow_forwardScientific studies have shown that the majority of human genetic differences worldwide exist within groups (or races) rather than between groups. True or false?arrow_forwardDiscuss the role of mutation in the origin of genetic polymorphisms. Suppose that a genetic polymorphism involves two alleles at frequencies of 0.45 and 0.55. Describe three different scenarios to explain these observed allele frequencies. You can propose that the mutations that produced the polymorphism are neutral, beneficial, or deleterious.arrow_forward
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