
Interpretation: For a given compound fluoxetine, it is to be prepared via two different methods of reductive amination
Concept Introduction:
Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions.
Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.
Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.
To find: Two different ways of preparing the given compound, fluoxetine via reductive amination.
Identify all C−N bonds in the given compound, fluoxetine

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Chapter 22 Solutions
Organic Chemistry 3rd.ed. Klein Evaluation/desk Copy