For a given set of compounds, amines are to be prepared via two different methods of reductive amination Concept Introduction : Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines. Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines. Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines. There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Gramicidin A can adopt more than one structure; NMR spectroscopy has revealed an “end-to-end” dimer form, and x-ray crystallography has revealed an “anti-parallel double- helical” form. Briefly outline and describe an experimentalapproach/strategy to investigate WHICH configuration (“end-to-end dimer” vs “anti-paralleldouble helical”) gramicidin adopts in an actual lipid bilayer.

Don't used hand raiting

CHEM2323 Problem 2-24 Tt O e: ל Predict the product(s) of the following acid/base reactions. Draw curved arrows to show the formation and breaking of bonds. If the bonds needed are not drawn out, you should redraw them. + BF3 (a) (b) HI + (c) OH -BF Problem 2-25 Use curved arrows and a proton (H+) to draw the protonated form of the following Lewis bases. Before starting, add all missing lone pairs. (a) (b) :0: (c) N 1 CHEM2323 PS CH02 Name:

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 6

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 7

Chapter 22.6, Problem 14PTS

(a)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 8

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 9

(b)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 10

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 11

(c)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 12

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 13

(d)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 14

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 15

(e)

Interpretation Introduction

Interpretation: For a given set of compounds, amines are to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride. It reduces the carbonyl group into amine group in a rapid way. So, it is called as reductive amination reactions. Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

There are two ways to get the starting compounds in either left or right side cleavage of all C−N bonds. After the cleavage, retrosynthetic analysis of the starting materials is done. If both aldehyde/ketone and amine starting materials are decided, reductive amination is followed in both the ways by placing the suitable reagents.

Answer 16

Expert Solution & Answer

Answer 17

Expert Solution & Answer

Answer 18

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 19

Ch. 22.2 - Prob. 1LTS Ch. 22.2 - Prob. 1PTS Ch. 22.2 - Prob. 2PTS Ch. 22.2 - Prob. 3ATS Ch. 22.3 - Prob. 4CC Ch. 22.3 - Prob. 5CC Ch. 22.3 - Prob. 6CC Ch. 22.3 - Prob. 7CC Ch. 22.3 - Prob. 8CC Ch. 22.3 - Prob. 9CC

Want to see the full answer?

Chapter 22 Solutions