Anatomy & Physiology
3rd Edition
ISBN: 9781259398629
Author: McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher: Mcgraw Hill Education,
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Chapter 22.3, Problem 9LO
Summary Introduction
To explain: The general functions of interferons.
Concept introduction: Cytokines are the chemical messengers that are produced by macrophages and activated T lymphocytes. They activate and help in the proliferation of B and T cells, and are involved in inflammation and to communicate between the cells. The general categories of cytokines include interleukin, tumor necrosis factor, colony-stimulating factor, and interferon.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 22 Solutions
Anatomy & Physiology
Ch. 22.1 - Prob. 1LOCh. 22.1 - Prob. 2LOCh. 22.1 - Which pathogen must enter a cell to replicate?...Ch. 22.2 - Prob. 3LOCh. 22.2 - Prob. 2WDLCh. 22.2 - Prob. 4LOCh. 22.2 - Prob. 5LOCh. 22.2 - What is the definition of a cytokine? How are...Ch. 22.2 - Prob. 6LOCh. 22.2 - Prob. 4WDL
Ch. 22.3 - Prob. 7LOCh. 22.3 - Prob. 5WDLCh. 22.3 - LEARNING OBJECTIVE
8. Describe the cells that...Ch. 22.3 - Prob. 6WDLCh. 22.3 - How do NK cells accomplish the task of eliminating...Ch. 22.3 - Prob. 9LOCh. 22.3 - Prob. 10LOCh. 22.3 - Prob. 11LOCh. 22.3 - Prob. 8WDLCh. 22.3 - Prob. 12LOCh. 22.3 - Prob. 13LOCh. 22.3 - Prob. 14LOCh. 22.3 - Prob. 1WDTCh. 22.3 - Prob. 9WDLCh. 22.3 - Prob. 10WDLCh. 22.3 - Prob. 15LOCh. 22.3 - Prob. 16LOCh. 22.3 - Prob. 11WDLCh. 22.3 - Prob. 12WDLCh. 22.4 - Prob. 17LOCh. 22.4 - Prob. 18LOCh. 22.4 - Prob. 19LOCh. 22.4 - Prob. 13WDLCh. 22.4 - What distinguishes a hapten from an antigen?Ch. 22.4 - Prob. 20LOCh. 22.4 - Prob. 2WDTCh. 22.4 - Prob. 15WDLCh. 22.4 - Prob. 21LOCh. 22.4 - LEARNING OBJECTIVE
22. Describe antigen-presenting...Ch. 22.4 - LEARNING OBJECTIVE
23. Explain the process of...Ch. 22.4 - Prob. 24LOCh. 22.4 - Which type of MHC class molecules is found on all...Ch. 22.4 - Prob. 25LOCh. 22.4 - Prob. 17WDLCh. 22.5 - Prob. 26LOCh. 22.5 - Prob. 18WDLCh. 22.5 - Prob. 27LOCh. 22.5 - Prob. 19WDLCh. 22.5 - Prob. 28LOCh. 22.5 - LEARNING OBJECTIVE
29. Describe the formation and...Ch. 22.5 - Prob. 20WDLCh. 22.6 - LEARNING OBJECTIVE
30. Describe how both helper...Ch. 22.6 - Prob. 21WDLCh. 22.6 - How do cytokines released by helper T-lymphocytes...Ch. 22.6 - LEARNING OBJECTIVE
31. Compare the activation of...Ch. 22.6 - Prob. 23WDLCh. 22.6 - Prob. 24WDLCh. 22.6 - Prob. 32LOCh. 22.6 - Prob. 25WDLCh. 22.7 - Prob. 33LOCh. 22.7 - Prob. 34LOCh. 22.7 - Prob. 35LOCh. 22.7 - Prob. 3WDTCh. 22.7 - Prob. 26WDLCh. 22.7 - Prob. 27WDLCh. 22.7 - Prob. 36LOCh. 22.7 - Prob. 37LOCh. 22.7 - Prob. 28WDLCh. 22.8 - Prob. 38LOCh. 22.8 - Prob. 29WDLCh. 22.8 - Prob. 39LOCh. 22.8 - What are the six major functions of antibodies?...Ch. 22.8 - Prob. 40LOCh. 22.8 - Which subclass of antibodies is most prevalent?...Ch. 22.9 - Prob. 41LOCh. 22.9 - Prob. 32WDLCh. 22.9 - Prob. 42LOCh. 22.9 - Prob. 33WDLCh. 22.9 - Prob. 43LOCh. 22.9 - LEARNING OBJECTIVE
44. Describe how both active...Ch. 22.9 - Prob. 34WDLCh. 22 - Prob. 1DYBCh. 22 - _____ 2. This cell releases cytokines to activate...Ch. 22 - _____ 3. This cell is activated by binding...Ch. 22 - _____ 4. These two cells destroy an infected cell...Ch. 22 - _____ 5. All of the following are functions of...Ch. 22 - Prob. 6DYBCh. 22 - _____ 7. During which process does additional...Ch. 22 - _____ 8. This chemical is released by...Ch. 22 - _____ 9. The correct sequence of the major events...Ch. 22 - Prob. 10DYBCh. 22 - Compare the general characteristics of innate...Ch. 22 - Define the inflammatory response, and explain its...Ch. 22 - Describe an antigen.Ch. 22 - Describe class I and class II MHC molecules, and...Ch. 22 - Prob. 15DYBCh. 22 - Prob. 16DYBCh. 22 - Explain the general function of cytotoxic...Ch. 22 - Describe both the function of antibodies and...Ch. 22 - There are two branches of adaptive immunity:...Ch. 22 - Prob. 20DYBCh. 22 - Prob. 1CALCh. 22 - Prob. 2CALCh. 22 - Prob. 3CALCh. 22 - Prob. 4CALCh. 22 - Prob. 5CALCh. 22 - Prob. 1CSLCh. 22 - Prob. 2CSLCh. 22 - Prob. 3CSL
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