ORGANIC CHEMISTRY (LL) W/ACCESS
ORGANIC CHEMISTRY (LL) W/ACCESS
4th Edition
ISBN: 9781119856122
Author: Klein
Publisher: WILEY
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Chapter 22, Problem 61PP
Interpretation Introduction

Interpretation: For a given compound benzphetamine, it is to be prepared via two different methods of reductive amination

Concept Introduction: Sodium cyanoborohydride is a strong reducing agent than sodium borohydride.  It reduces the carbonyl group into amine group in a rapid way.  So, it is called as reductive amination reactions.  Aldehyde or ketone group is reacted with ammonia in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce primary amines.

ORGANIC CHEMISTRY (LL) W/ACCESS, Chapter 22, Problem 61PP , additional homework tip  1

Aldehyde or ketone group is reacted with primary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce secondary amines.

ORGANIC CHEMISTRY (LL) W/ACCESS, Chapter 22, Problem 61PP , additional homework tip  2

Aldehyde or ketone group is reacted with secondary amine in the presence of sodium cyanoborohydride as a reducing agent and a proton source in the reaction medium to produce tertiary amines.

ORGANIC CHEMISTRY (LL) W/ACCESS, Chapter 22, Problem 61PP , additional homework tip  3

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Chapter 22 Solutions

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