(a) Interpretation: The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined. Concept introduction: Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

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Answer 1

Question

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

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The beta-lactamase hydrolyzes the lactam-ring in penicillin. Describe the mechanism of hydrolysis, insuring to include the involvement of S, D, & K in the reaction sequence. Please help

To map the active site of beta-lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Why doesn't D in this hexapeptide not participate in the hydrolysis of the beta-lactam ring even though S, K, and D are involved in the catalyst?

To map the active site of -lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Using the experimental results described above derive the primary sequence of the active site hexapeptide. Please help!

Answer 2

Question

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

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Answer 3

Question

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

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Answer 4

Question

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

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Answer 5

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 6

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 7

Chapter 22, Problem 59P

Interpretation Introduction

(a)

Interpretation:

The effect of soraphen A and its varying concentration on the fatty acid synthesis should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The effect of soraphen A on fatty acid oxidation must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 10

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 11

Interpretation Introduction

(c)

Interpretation:

The results of graph B should be explained keeping in mind that sorpahen A inhibits acetyl CoA carboxylase.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 12

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 13

Interpretation Introduction

(d)

Interpretation:

The effect on phospholipid synthesis by inhibition of carboxylase must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 14

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 15

Interpretation Introduction

(e)

Interpretation:

The effect of phospholipid synthesis on cell’s viability must be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 16

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 17

Interpretation Introduction

(f)

Interpretation:

The result of soraphen A on cancer cell viability should be determined.

Concept introduction:

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme, which catalyzes the conversion of acetyl-CoA into malonyl-CoA, in the presence of bicarbonate ion. It has two catalytic activities, carboxyltransferase and biotin carboxylase. This enzyme is found in the chloroplasts of the plants, and endoplasmic reticulum of the animals. The main motive of ACC is to synthesize malonyl CoA for the synthesis of fatty acids.

Answer 18

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Answer 19

Expert Solution & Answer

Answer 20

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Answer 21

Ch. 22 - Prob. 1P Ch. 22 - Prob. 2P Ch. 22 - Prob. 3P Ch. 22 - Prob. 4P Ch. 22 - Prob. 5P Ch. 22 - Prob. 6P Ch. 22 - Prob. 7P Ch. 22 - Prob. 8P Ch. 22 - Prob. 9P Ch. 22 - Prob. 10P

Solution Summary: The author explains that soraphen A inhibits the fatty acid synthesis process. It is an inhibitor of acetyl CoA carboxylase.

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Chapter 22 Solutions