Concepts of Genetics (11th Edition)
Concepts of Genetics (11th Edition)
11th Edition
ISBN: 9780321948915
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 22, Problem 3NST
Summary Introduction

To determine: The sequence of the probe that will hybridize the ASO sequence.

Introduction: Allele-specific oligonucleotide (ASO) is a short synthetic DNA which is complementary to the sequence of target DNA. ASO analysis is done under conditions that facilitate only complementary nucleotide sequences to hybridize to the ASO on the membrane.

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