Role of Arg-22 in the conformational state change between the R and T state. Introduction: Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

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Answer 1

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Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

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Fructose 1,6-bisphosphatase (FBPase) is a key enzyme in gluconeogenesis. The mammalian enzyme is tetrameric, negatively regulated by both Fructose 2,6-bisphosphate and AMP. Propose three (3) distinct models for how these molecules regulate FBPase activity. Also, describe how the enzyme might differentiate between Fructose 1,6 bisphosphate and Fructose 2,6-bisphosphate binding to the allosteric site on the enzyme with particular emphasis on amino acids comprising the allosteric binding site(s).

Propose a mechanism for the conversion of glucose 6-phosphate into fructose 6- phosphate by phosphoglucose isomerase based on the mechanism of triose phosphate isomerase.

Consider the complete oxidation of one mole of simple TAG containing behenic acid residues (22:0). I. For one mole of the fatty acid residue, determine the following: c. What is the number of ATP yield obtained from FADH2 coming from the complete β-oxidation of the fatty acid residue

Answer 2

Question

Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

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Answer 3

Question

Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Expert Solution & Answer

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Answer 4

Question

Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Expert Solution & Answer

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Answer 5

Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Answer 6

Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Answer 7

Chapter 22, Problem 22P

Interpretation Introduction

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Answer 8

Expert Solution & Answer

Answer 9

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Answer 10

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Answer 11

Ch. 22 - Prob. 1P Ch. 22 - Prob. 2P Ch. 22 - Prob. 3P Ch. 22 - Prob. 4P Ch. 22 - Prob. 5P Ch. 22 - Prob. 6P Ch. 22 - Prob. 7P Ch. 22 - Prob. 8P Ch. 22 - Prob. 9P Ch. 22 - Understanding Enzyme Mechanisms Related to...

Role of Arg-22 in the conformational state change between the R and T state. Introduction: Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Solution Summary: The author explains the role of Arg-22 in the conformational state change between the R and T state of the enzyme.

Concept explainers

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Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Want to see the full answer?

Chapter 22 Solutions

Role of Arg-22 in the conformational state change between the R and T state. Introduction: Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Solution Summary: The author explains the role of Arg-22 in the conformational state change between the R and T state of the enzyme.

Concept explainers

Videos

Interpretation: Role of Arg-22 in the conformational state change between the R and T state. Introduction: Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.

Want to see the full answer?

Chapter 22 Solutions

Interpretation:

Role of Arg-22 in the conformational state change between the R and T state.

Introduction:

Fructose-1,6-bisphosphatase enzyme is involved in the fructose-1,6-bisphosphate to fructose 6-phosphate conversion that takes place in the gluconeogenesis and the Calvin cycle.