Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Question
thumb_up100%
Chapter 22, Problem 17P
Interpretation Introduction
To explain:
How pentose phosphate pathway and the glycolytic pathway can combine and produce both NADPH and ATP without producing ribose-5-phosphate.
Introduction:
NADPH is produced in Pentose phosphate pathway of by oxidation but ATP is produced in glycolytic pathway by non-oxidation.
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Considering the complete oxidation of an 18-C fatty acid. Give the answer to the following question.a. What is the total number of NADH produced in TCA if all of the acetyl CoA enters the cycle?
b. What is the total number of FADH2 produced in TCA if all the acetyl CoA enters the cycle?c. How much ATP is produced in the overall oxidation?
Which statement does NOT describe a general function of the pentose phosphate pathway?
Group of answer choices
The pentose phosphate pathway is used to produce NADPH for reductive biosynthesis in adipocytes.
The pentose phosphate pathway allows for the entry of dietary pentose intermediates into the glycolytic pathway.
The pentose phosphate pathway produces reduced molecules whose electrons may be shuttled to the mitochondria for oxidative phosphorylation.
The pentose phosphate pathway allows for the conversion of hexoses into pentoses that may be used as precursors in the synthesis of nucleosides.
How many ATP are produced by substrate level phosphorylation ONLY in the complete oxidation of activated palmitate (C16:0 fatty acyl CoA) in a skeletal muscle cell
Chapter 22 Solutions
Biochemistry
Ch. 22 - Prob. 1PCh. 22 - Prob. 2PCh. 22 - Prob. 3PCh. 22 - Prob. 4PCh. 22 - Prob. 5PCh. 22 - Prob. 6PCh. 22 - Prob. 7PCh. 22 - Prob. 8PCh. 22 - Prob. 9PCh. 22 - Understanding Enzyme Mechanisms Related to...
Ch. 22 - Understanding the Mechanisms of Reactions Related...Ch. 22 - Prob. 12PCh. 22 - Prob. 13PCh. 22 - Prob. 14PCh. 22 - Prob. 15PCh. 22 - Prob. 16PCh. 22 - Prob. 17PCh. 22 - Prob. 18PCh. 22 - Prob. 19PCh. 22 - Prob. 20PCh. 22 - Prob. 21PCh. 22 - Prob. 22PCh. 22 - Using the ActiveModel for aldose reductase,...
Knowledge Booster
Similar questions
- Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.arrow_forwardSonicating a suspension of mitochondria produces submitochondrial particles derived from the innermitochondrial membrane. These membranous vesicles seal inside out, so that the intermembrane space of themitochondria becomes the lumen of the submitochondrial particle. Explain (or diagram) the process of electrontransfer and oxidative phosphorylation in these particles. Assuming all the substrates for oxidativephosphorylation are present in excess, does ATP synthesis increase or decrease with an increase in the pH ofthe fluid in which the submitochondrial particles are suspended? Why?arrow_forwardHow many ATP can be produced from the catabolism of one glucose molecule. (Assume that each NADH produces 2.5 ATP, and each FADH2 produces 1.5 ATP, and that NADH produced in glycolysis use the glycerol 3-phosphate shuttle.)arrow_forward
- A person with a hereditary deficiency realated to mitochondrial fatty acid oxidation shows accumulation of a long-chain acylcarnitine in the mi- tochondrial matrix. What factor could be responsible for this disorder? Provide a biochemical explanation for its mechanism of action.arrow_forwardIn the fatty acid degradation of the following molecule: How many Acetyl CoA, NADH, and FADH2 will be generated? Will the fatty acid degradation result in the generation of propionyl CoA?arrow_forwardConsidering the complete oxidation of an 18-C fatty acid. Give the answer for the following question.a. How many rounds of beta-oxidation is needed?b. How many NADH molecules are produced in beta-oxidation only?c. How many FADH2 molecules are produced in beta-oxidation only?d. How many Acetyl Co-A are produced?arrow_forward
- Briefly explain the malate-aspartate shuttle. Distinguish between this shuttle with the glycerol -phosphate shuttle based upon their transport of reducing equivalents and their potential for ATP synthesis.arrow_forwardFatty acid oxidation for energy yield occurs in the mitochondrial matrix, and for palmitate as one example, generates [ Select ] ["FADH2, NADH, and Acetyl-CoA", "FADH, GTP and NADPH"] , all of which can be converted to ATP (108 of them to be exact) via oxidative phosphorylation. This is a [ Select ] ["greater", "smaller"] yield of ATP per carbon atom compared to glucose. Ketogenesis is a process where acetyl-CoA (including that from breakdown of fatty acids) is converted to ketone bodies under conditions where carbohydrates are [ Select ] ["in excess", "limiting"] . Acetoacetate and D-beta-hydroxybutyrate are delivered from liver to the bloodstream where they provide energy for [ Select ] ["cardiac and skeletal muscle as well as brain", "synthesis of glycogen"]. [ Select ] ["Insulin", "Glucagon"] promotes ketogenesis by stimulating fatty acid export from adipose tissue.arrow_forwardThe regulation of 1-phosphofructokinase occurs primarily by allosteric effectors, including ATP and ADP. Given that phosphofructokinase activity is necessary for glycolysis to proceed, predict what effect ATP would have. How about ADP?arrow_forward
- Deoxynucleotides (deoxynucleoside triphosphates) are the substrates for DNA synthesis. Calculate the number of glucose molecules that must be degraded to generate the energy required for the synthesis of 1000 deoxynucleotides used in DNA synthesis. Assume that glucose is oxidized completely to CO2 and H2O, the malate–aspartate shuttle is in operation, and NADPH is the equivalent of 4 ATParrow_forwardEthanol as a Source of Metabolic Energy (Integrates with Chapters 19 and 20.) Acetate produced in ethanol metabolism can be transformed into acetyl-COA by the acetyl thiokinase reaction: Acetate+ATP+CoASHacetyleCoA+AMP+PPiAcetyle-CoA then can enter the citric acid cycle and undergo oxidation to 2 CO2by this route, assuming oxidative phosphorylation is part of the process? (Assume all reactions prior to acetyl-CoA entering the citric acid cycle occur outside the mitochondrion). Per carbon atom, which is a better metabolic fuel, ethanol or glucose? That is, how many ATP equivalents per carbon atom are generated by combustion of glucose versus ethanol to CO2?arrow_forwardActivation of the fatty acid (converting it to fatty acyl-SCoA) requires the expenditure of 2 ATPs. Use your answers from parts B and C to calculate the total number of ATPs generated from the metabolism of a saturated fatty acid with 18 carbon atoms including both the citric acid cycle and the ββbeta-oxidation pathway as well as the initial ATP required to produce the acyl-SCoA molecule that starts the process. Express your answer as an integer.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning