Chapter 22, Problem 22.20P

Interpretation Introduction

(a)

Interpretation:

The structure of enolate formed by the treatment of $2,2-\text{dimethylcyclohexanone}$ with LDA is to be stated. The aldol product of $2,2-\text{dimethylcyclohexanone}$ with acetaldehyde is to be stated.

Concept introduction:

In aldol condensation reaction, the base abstracts an acidic proton from the carbon atom to form enolate. This enolate or enol reacts with carbonyl compound that leads to the formation of hydroxyaldehyde or hydroxyketone which on further dehydration gives the conjugated enone.

Interpretation Introduction

(b)

Interpretation:

Whether the diastereomers of the product are formed in equal or in different amounts is to be stated.

Concept introduction:

Diastereomers are the type of stereoisomers that are non identical, non super imposable mirror images of each other. Diastereomers can have different physical and chemical properties. They must have two stereocentes.