Synthesis of glycogen particle is done by Tyr 1 9 4 of glycogenin which reacts with glucose unit and produce tyrosyl glucose. UDP-glucose produces glucose unit. This complete reaction is catalyzing by the glycogenin. Working mechanism of this reaction is to be explained. Concept introduction: Complete mechanism is described by nucleophilic attack of aspartate which is residue of catalyst glycogenin.

Question

An organic chemist ordered the wrong item. She wanted to obtain 1-hydroxy-2-butanone, butinstead ordered 2-hydroxybutyraldehyde. As a good biochemist, show how the organic chemistcould use biological catalysis to make her desired compound.

Answer 1

Question

Chapter 22, Problem 19P

Interpretation Introduction

Interpretation:

Synthesis of glycogen particle is done by Tyr¹⁹⁴of glycogenin which reacts with glucose unit and produce tyrosyl glucose. UDP-glucose produces glucose unit. This complete reaction is catalyzing by the glycogenin. Working mechanism of this reaction is to be explained.

Concept introduction:

Complete mechanism is described by nucleophilic attack of aspartate which is residue of catalyst glycogenin.

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