The addition of Grignard reagent to an ester or a nitrile to synthesize 4 -phenylheptan- 4 -ol is to be explained. Concept introduction: The grignard reagent is used to generate R − carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

First I wanted to see if you would mind checking my graphs behind me. (They haven't been coming out right)? Second, could you help me explain if the rate of reaction is proportional to iodide and persulfate of each graph. I highlighted my answer and understanding but I'm not sure if I'm on the right track. Thank you in advance.

The heat of combustion for ethane, C2H6C2H6 , is 47.8 kJ/g. How much heat is produced if 1.65 moles of ethane undergo complete combustion?

Review of this week's reaction: H2NCN (cyanamide) + CH3NHCH2COOH (sarcosine) + NaCl, NH4OH, H2O ----> H2NC(=NH)N(CH3)CH2COOH (creatine) Q7. Draw by hand the reaction of creatine synthesis listed above using line structures without showing the Cs and some of the Hs, but include the lone pairs of electrons wherever they apply. (4 pts) Q8. Considering the Zwitterion form of an amino acid, draw the Zwitterion form of Creatine. (2 pts) Q9. Explain with drawing why the C—N bond shown in creatine structure below can or cannot rotate. (3 pts)

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Answer 6

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 7

Chapter 21.9, Problem 21.28P

(a)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize 4-phenylheptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize heptan-4-ol is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks on electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the carbonyl group into alcohol.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The addition of Grignard reagent to an ester or a nitrile to synthesize pentan-2-one is to be explained.

Concept introduction:

The grignard reagent is used to generate R− carbanion which attacks electron deficient center. Carbonyl group that has good leaving group gives substituted products. This reagent is used to convert the nitrile group into ketone group.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 15

Ch. 21.2F - Name the following carboxylic acid derivatives,...Ch. 21.4A - Prob. 21.2P Ch. 21.4A - Prob. 21.3P Ch. 21.4A - Prob. 21.4P Ch. 21.5C - Prob. 21.7P Ch. 21.6 - When ethyl 4-hydroxybutyrate is heated in the...Ch. 21.6 - Propose a mechanism for the following ring-opening...Ch. 21.6 - Prob. 21.15P Ch. 21.7B - Prob. 21.16P Ch. 21.7C - Prob. 21.19P

Solution Summary: The author explains the mechanism of the addition of Grignard reagent to an ester or a nitrile to synthesize heptan- 4 -ol.

Want to see the full answer?

Chapter 21 Solutions