Biochemistry
9th Edition
ISBN: 9781305961135
Author: Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher: Cengage Learning
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Chapter 21, Problem 50RE
REFLECT AND APPLY A drug that reduces blood cholesterol has the effect of stimulating the production of bile salts. How might this result in lower blood cholesterol? Hint: There are two ways.
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Chapter 21 Solutions
Biochemistry
Ch. 21 - REFLECT AND APPLY (a) The major energy storage...Ch. 21 - RECALL What is the difference between...Ch. 21 - RECALL How are lipases activated hormonally?Ch. 21 - RECALL What is the metabolic purpose of linking a...Ch. 21 - RECALL Outline the role of carnitine in the...Ch. 21 - RECALL What is the difference between the type of...Ch. 21 - RECALL Draw a six-carbon saturated fatty acid and...Ch. 21 - REFLECT AND APPLY Why does the degradation of...Ch. 21 - REFLECT AND APPLY Given the nature of the hormonal...Ch. 21 - RECALL Compare the energy yields from the...
Ch. 21 - RECALL Which generates more ATPthe processing of...Ch. 21 - MATHEMATICAL Calculate the ATP yield for the...Ch. 21 - REFLECT AND APPLY It is frequently said that...Ch. 21 - RECALL Describe briefly how -oxidation of an...Ch. 21 - RECALL You hear a fellow student say that the...Ch. 21 - RECALL What are the unique enzymes needed to...Ch. 21 - RECALL What are the unique enzymes needed to...Ch. 21 - MATHEMATICAL Calculate the net ATP yield from the...Ch. 21 - MATHEMATICAL Calculate the net ATP yield from...Ch. 21 - MATHEMATICAL Calculate the net ATP yield from...Ch. 21 - REFLECT AND APPLY How many cycles of -oxidation...Ch. 21 - REFLECT AND APPLY It has been stated many times...Ch. 21 - RECALL Under what conditions are ketone bodies...Ch. 21 - RECALL Briefly outline the reactions involved in...Ch. 21 - REFLECT AND APPLY Why might a doctor smell the...Ch. 21 - REFLECT AND APPLY Why might a person who is an...Ch. 21 - REFLECT AND APPLY A friend who is trying to lose...Ch. 21 - RECALL Compare and contrast the pathways of fatty...Ch. 21 - RECALL Outline the steps involved in the...Ch. 21 - RECALL What is the metabolic importance of...Ch. 21 - RECALL In fatty acid degradation, we encounter...Ch. 21 - RECALL How are the two redox reactions of...Ch. 21 - RECALL How is ACP similar to coenzyme A? How is it...Ch. 21 - RECALL What is the purpose of having ACP as a...Ch. 21 - RECALL Why are linoleate and linolenate considered...Ch. 21 - REFLECT AND APPLY Is it possible to convert fatty...Ch. 21 - REFLECT AND APPLY What is the role of citrate in...Ch. 21 - REFLECT AND APPLY In the mitochondrion is a...Ch. 21 - REFLECT AND APPLY In fatty acid synthesis,...Ch. 21 - REFLECT AND APPLY (a) Where in an earlier chapter...Ch. 21 - RECALL What is the source of the glycerol in...Ch. 21 - RECALL What is the activating group used in the...Ch. 21 - RECALL What are the differences between synthesis...Ch. 21 - RECALL How are isoprene units important in...Ch. 21 - RECALL A cholesterol sample is prepared using...Ch. 21 - Prob. 46RECh. 21 - Prob. 47RECh. 21 - Prob. 48RECh. 21 - Prob. 49RECh. 21 - REFLECT AND APPLY A drug that reduces blood...Ch. 21 - RECALL What role does neuropeptide Y play in...Ch. 21 - Prob. 52RECh. 21 - Prob. 53RECh. 21 - Prob. 54RECh. 21 - RECALL What is the connection between insulin and...
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- REFLECT AND APPLY Albert Szent-Gyorgi, a pioneer in early photosynthesis research, stated, What drives life is a little electric current, kept up by the sunshine. What did he mean by this?arrow_forwardREFLECT AND APPLY Sulfanilamide and related sulfa drugs were widely used to treat diseases of bacterial origin before penicillin and more advanced drugs were readily available. The inhibitory effect of sulfanilamide on bacterial growth can be reversed by p-aminobenzoate. Suggest a mode of action for sulfanilamide.arrow_forwardREFLECT AND APPLY Why can we say that having a pure non- competitive inhibitor present is similar to just having less enzyme present?arrow_forward
- REFLECT AND APPLY A mutation that changes an alanine residue in a protein to an isoleucine leads to a loss of activity. Activity is regained when a further mutation at the same site changes the isoleucine to a glycine. Why?arrow_forwardREFLECT AND APPLY When we compare the binding of I and of S to the enzyme in a mixed noncompetitive inhibitor, we assumed that the binding of I decreased the affinity of the enzyme for S. What would happen if the opposite were true?arrow_forwardREFLECT AND APPLY Noncompetitive inhibition is a limiting case in which the effect of binding inhibitor has no effect on the affinity for the substrate and vice versa. Suggest what a LineweaverBurk plot would look like for an inhibitor that had a reaction scheme similar to that on page 159 (noncompetitive inhibition reaction), but where binding inhibitor lowered the affinity of EI for the substrate.arrow_forward
- REFLECT AND APPLY The enzyme D-amino acid oxidase has a very high turnover number because the D-amino acids are potentially toxic. The KM for the enzyme is in the range of 1 to 2 mM for the aromatic amino acids and in the range of 15 to 20 mM for such amino acids as serine, alanine, and the acidic amino acids. Which of these amino acids are the preferred substrates for the enzyme?arrow_forwardREFLECT AND APPLY You are studying with a friend who is describing the Bohr effect. She tells you that in the lungs, hemoglobin binds oxygen and releases hydrogen ion; as a result, the pH in- creases. She goes on to say that in actively metabolizing muscle tissue, hemoglobin releases oxygen and binds hydrogen ion and, as a result, the pH decreases. Do you agree with her reasoning? Why or why not?arrow_forwardREFLECT AND APPLY Chemotherapy patients receiving cytotoxic (cell-killing) agents such as FdUMP (the UMP analogue that contains fluorouracil) and methotrexate temporarily go bald. Why does this take place?arrow_forward
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