EBK ESSENTIAL ORGANIC CHEMISTRY
EBK ESSENTIAL ORGANIC CHEMISTRY
3rd Edition
ISBN: 8220100659461
Author: Bruice
Publisher: PEARSON
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Chapter 21, Problem 31P

The amino acid sequences of peptide fragments obtained from a normal protein were compared with those obtained from the same protein synthesized by a defective gene. They were found to differ in only one peptide fragment. Their amino acid sequences are shown here:

    Normal: Gln-Tyr-Gly-Thr-Arg-Tyr-Val

    Mutant: Gln-Ser-Glu-Pro-Gly-Thr

  1. a. What is the defect in DNA?
  2. b. It was later determined that the normal peptide fragment is an octapeptide with a C-terminal Val-Leu. What is the C-terminal amino acid of the mutant peptide?
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EBK ESSENTIAL ORGANIC CHEMISTRY

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