Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 21, Problem 26CTQ
One of the first and most important targets for drugs to fight infection with HIV (a retrovirus) is the reverse transcriptase enzyme. Why?
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Why can protease inhibitors and nucleoside analogs be used in minimizing the replication of the HIV virus?
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Chapter 21 Solutions
Biology 2e
Ch. 21 - Figure 21.5 Which of the following statements...Ch. 21 - Figure 21.8 Influenza virus is packaged in a viral...Ch. 21 - Figure 21.10 Which of the following statements is...Ch. 21 - Which statement is true? A virion contains DNA and...Ch. 21 - The viral______play(s) a role in attaching a...Ch. 21 - Viruses. all have a round shape cannot have a long...Ch. 21 - The observation that the bacteria genus Chlamydia...Ch. 21 - A scientist discovers a new virus with a linear,...Ch. 21 - Which statement is not true of viral replication?...Ch. 21 - Which statement is true of viral replication? In...
Ch. 21 - Which statement is true of reverse transcriptase?...Ch. 21 - Oncogenic virus cores can be. RNA DNA neither RNA...Ch. 21 - Which is true of DNA viruses? They use the host...Ch. 21 - A bacteriophage can infect the lungs viruses...Ch. 21 - People with the CCR5?32 mutation of a T-cell...Ch. 21 - An apple grower notices that several of his apple...Ch. 21 - Which of the following is NOT used to treat active...Ch. 21 - Vaccines. are similar to viroids are only needed...Ch. 21 - A patient presents at the clinic with an acute...Ch. 21 - Which of the following is not associated with...Ch. 21 - Which statement is true of viroids? They are...Ch. 21 - The first electron micrograph of a virus (tobacco...Ch. 21 - Varicella-zoster virus is a double-stranded DNA...Ch. 21 - Classify the Rabies virus (a rhabdovirus family...Ch. 21 - Why can’t dogs catch the measles?Ch. 21 - One of the first and most important targets for...Ch. 21 - In this section, you were introduced to different...Ch. 21 - Although plant viruses cannot infect humans, what...Ch. 21 - A bacteriophage with a lytic life cycle develops a...Ch. 21 - Why is immunization after being bitten by a rabid...Ch. 21 - The vaccine Gardasil that targets human papilloma...Ch. 21 - Prions are responsible for variant Creutzfeldt...Ch. 21 - How are viroids like viruses?Ch. 21 - A botanist notices that a tomato plant looks...
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Similar questions
- Why is HIV called a retrovirus?arrow_forwardWhich of the following models best depicts how the genetic information in a retrovirus is eventually translated into proteins? A) DNA in the retrovirus → RNA in the host cell → Proteins B) RNA in the retrovirus → DNA in the host cell → RNA in the host cell → Proteins C) RNA in the retrovirus → mRNA in the host cell → Proteins D) DNA in the retrovirus → mRNA in the host cell → Proteinsarrow_forwardWhen Wimmer and coworkers announced that they had synthesized the poliovirus, they created considerable controversy. Some people feared that deadly and highly contagious viruses might be synthesized by bioterrorists. The researchers responded that they were merely applying current knowledge and techniques to demonstrate the principle that viruses are basically chemical entities that can be synthesized in the laboratory. Do you think scientists should synthesize viruses or other agents that can cause infectious disease? What are the implications of forbidding such research?arrow_forward
- Answer the following 1.Are viruses living or non-living organisms? 2. What is the difference between HIV and AIDS? 3. HIV is classified as a retrovirus. What are retroviruses? 4. In your own words, provide a short summary of the HIV replication cycle. 5. Why is reverse transcriptase an important enzyme in the replication cycle of HIV? 6. In the chapter about enzymes, we have discussed how drugs are basically inhibitors. There are currently a multitude of Antiretroviral therapy (ART or ARV) options available to people living with HIV (PLHIV) so that the viral replication is suppressed and does not progress to AIDS. What do you think these drugs target? Discuss briefly. 7. SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? 8. In your own opinion, do…arrow_forwardWhich of the following are the functions of reverse transcriptase in retroviruses? i) it hydrolyzes the host cell's DNA ii) it uses viral RNA as a template for DNA synthesis iii) it converts host cell RNA into viral DNA iv) it translates viral RNA into proteins v) It uses viral RNA as a template for making complementary RNA strand vi) It degrades RNA from DNA-RNA hybrid Oi, iv and v O ii, iv, v and vi ii and iii ii and viarrow_forwardWhich of the following is not a component of HIV?a) Proteasesb) Ribosomesc) Reverse transcriptased) Proteine) RNAarrow_forward
- What enzyme is responsible for the production of viral DNA from a retrovirus?arrow_forwardTrue or False: There are antibiotics that target viruses?arrow_forwardAn antimicrobial drug binds to the HIV reverse transcriptase enzyme, preventing it from working. Which of the following is true of this drug? It would inhibit early replication steps of some viruses, but not affect normal eukaryotic cell activity. It would directly interfere with translation of some viral proteins and some eukaryotic proteins. It would block assembly/maturation steps of some viruses, and interfere with translation in eukaryotic cells. It would interfere with release of newly formed viruses from a host cell, but not affect eukaryotic cells. It would interfere with protein synthesis in bacteria, but not affect eukaryotic ribosomes. It would interfere with mRNA transcription in bacteria and viruses, but not affect eukaryotic transcription.arrow_forward
- What is the function of reverse transcriptase in retroviruses? a) It converts viral RNA into double-stranded DNA Ob) It uses viral RNA as a template for making complementary RNA strands Oc) It translates viral RNA into proteins d) It uses viral DNA as a template for RNA synthesisarrow_forwardWhich of the following highly contagious viruses is a single-stranded ribonucleic acid (RNA) virus with a helical capsid and envelope and is transmitted by coming in contact with respiratory secretions? "This is a highly contagious respiratory illness transmitted when an infected person coughs or sneezes virus particles into the air," the health department said in a written statement. "It's so contagious that if one person is sick and spreading measles, nine out of 10 people around them who aren't immune will get it, too." Group of answer choices a. Measles b. Parvovirus c. Coxsackie virus A d. Rhinovirusarrow_forwardHow do you kill a virus artificially?arrow_forward
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