Concept explainers
Medical Moment
The Making of the Flu Vaccine: An Example of a Live Growth Medium
Have you ever wondered why health care workers ask about allergic reactions to eggs prior to immunizing patients? Live attenuated vaccines are sometimes created by culturing a virus, such as the influenza virus, in live animals, often chick embryos. The virus is inoculated into fertilized eggs, which are then incubated to encourage the replication of large numbers of virus particles. The contents of the eggs are then collected and purified to create the vaccine.
Today, influenza vaccine preparations contain such low levels of egg protein trial they can be safely administered even in most individuals with allergies though it is recommended that they be medically monitored after receiving the dose. Vaccines in which the virus has been grown in cell culture, rather than in chicken eggs, are also available.
Q. Based on the information here, do you think that influenza viruses can infect (adult) birds? Why or why not?
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Microbiology Fundamentals: A Clinical Approach
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